“…Patients with certain hematologic malignancies, organ transplants, HIV, pharmacologic immunosuppression, and certain genodermatoses are at higher risk of developing SCC [28][29][30][31]. Moioli et al recently noted a non-significant, but higher percentage of residual SCCis or SCC in serially sectioned excision specimens of biopsy-proven SCCis from immunosuppressed patients [32]. The rate of complete tumor clearance after biopsy was significantly lower in immunosuppressed patients than in immunocompetent patients.…”