Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: from novelty to routine in selected cases

Moran, Brendan

doi:10.1007/s10151-017-1679-8

Cited by 3 publications

(1 citation statement)

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“…Tumour cytoreductive surgery with a satisfactory tumour reduction ratio can prolong the survival time of patients and improve their overall survival rate. However, the scope of surgical resection includes not only ovaries, uterus and omentum but also pelvic and abdominal metastases and affected lymph nodes with a diameter of > 2 cm[ 9 ]. The operation is challenging, the injury obtained from the procedure is significant, and there are numerous complications since the procedure often involves the intestinal tract, the urinary tract and pelvic vessels.…”

Section: Introductionmentioning

confidence: 99%

Machine learning-assisted ensemble analysis for the prediction of urinary tract infection in elderly patients with ovarian cancer after cytoreductive surgery

et al. 2022

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BACKGROUND Urinary tract infection (UTI) is a common type of postoperative infection following cytoreductive surgery for ovarian cancer, which severely impacts the prognosis and quality of life of patients. AIM To develop a machine learning assistant model for the prevention and control of nosocomial infection. METHODS A total of 674 elderly patients with ovarian cancer who were treated at the Department of Gynaecology at Jingzhou Central Hospital between January 31, 2016 and January 31, 2022 and met the inclusion criteria of the study were selected as the research subjects. A retrospective analysis of the postoperative UTI and related factors was performed by reviewing the medical records. Five machine learning-assisted models were developed using two-step estimation methods from the candidate predictive variables. The robustness and clinical applicability of each model were assessed using the receiver operating characteristic curve, decision curve analysis and clinical impact curve. RESULTS A total of 12 candidate variables were eventually included in the UTI prediction model. Models constructed using the random forest classifier, support vector machine, extreme gradient boosting, and artificial neural network and decision tree had areas under the receiver operating characteristic curve ranging from 0.776 to 0.925. The random forest classifier model, which incorporated factors such as age, body mass index, catheter, catheter intubation times, blood loss, diabetes and hypoproteinaemia, had the highest predictive accuracy. CONCLUSION These findings demonstrate that the machine learning-based prediction model developed using the random forest classifier can be used to identify elderly patients with ovarian cancer who may have postoperative UTI. This can help with treatment decisions and enhance clinical outcomes.

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Section: Introductionmentioning

confidence: 99%