Optical Coherence Tomography Angiography Features of Iris Racemose Hemangioma in 4 Cases

Chien, Jason L; Sioufi, Kareem; Ferenczy, S; Say, Emil Anthony T.; Shields, Carol L.

doi:10.1001/jamaophthalmol.2017.3390

Cited by 28 publications

(21 citation statements)

References 13 publications

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“…Iris haemangioma is detected anterior to normal radial vessel and appears as a dilated vessel with U-shaped course from the peripheral iris, forming a tortuous loop near pupil and ending again near the limbal area [ 69 ]. The pinpoint vessels of ocular surface squamous neoplasia are also visible in OCTA [ 67 ].…”

Section: Anterior Segment Tumoursmentioning

confidence: 99%

Optical coherence tomography angiography (OCTA) applications in ocular oncology

Naseripour

Falavarjani

Mirshahi

et al. 2020

Eye

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Optical coherence tomography angiography (OCTA) is a revolutionary method in the visualization of the vascular system in different retinal and choroidal layers. During the last 4 years since the commercial availability of different OCTA devices, attempts have been made to utilize this technology in various aspects of ocular oncology from the differentiation of benign and malignant lesions to assisting in evaluation of post-treatment complications, such as radiation retinopathy. However, current OCTA technology is restricted by various artefacts and inherent limitations, some of which are more pronounced in the presence of elevated tumoural lesions. Imminent advancements in OCTA systems and image acquisition processes promise a great potential for application of OCTA in ocular oncology.

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Section: Anterior Segment Tumoursmentioning

confidence: 99%

Optical coherence tomography angiography (OCTA) applications in ocular oncology

Naseripour

Falavarjani

Mirshahi

et al. 2020

Eye

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“…It is commonly used for imaging the retinal vasculature [6–9]. Recently, OCTA has been employed in imaging the anterior segment of the eye for aiding the diagnosis of vascular lesions of the conjunctiva, cornea, and iris [10–13]. While the analysis of vessel density in the retina was reported in many previous studies [14–16], the vessel density of the anterior segment was reported in several publications [10, 17–21].…”

Section: Introductionmentioning

confidence: 99%

Quantitative analysis of conjunctival microvasculature imaged using optical coherence tomography angiography

et al. 2019

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BackgroundThe goal was to quantitatively analyze the bulbar conjunctival microvascular density using optical coherence tomography angiography (OCTA) and compare it to the vessel density using functional slit-lamp biomicroscopy (FSLB).MethodsTemporal bulbar conjunctiva of 20 eyes (10 healthy subjects) was imaged using both OCTA and FSLB. Image processing was performed including equalization, de-noising, thresholding, and skeletonization. The vessel density was measured by fractal analysis (box counting, Dbox) and pixel counting (%).ResultsVessel density (Dbox) of the bulbar conjunctiva obtained using OCTA was 1.28 ± 0.01 Dbox, which was significantly lower than the result (1.32 ± 0.01 Dbox, P < 0.001) obtained using FSLB. Furthermore, the vessel density (%) obtained using OCTA was 3.31 ± 0.12%, which was also significantly lower than the result (3.69 ± 0.16%, P < 0.001) obtained using FSLB. No significant correlations (r ranged from 0.21 to 0.32, P > 0.05) between both instruments were found in both vessel density methods (Dbox and percentage). However, in each of the devices, vessel density in Dbox was significantly correlated with the vessel density in percentage (r = 1.0 for FSLB and r = 0.98 for OCTA, both P < 0.001).ConclusionThis study demonstrated that the vessel density of the bulbar conjunctiva obtained using OCTA can be quantified, and the results were not compatible with that obtained using slit-lamp biomicroscopy photography.

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“…Notably, AS-OCTA provided quantitative iris vascular density analysis. Over the last years, various authors have described the AS-OCTA technique in iris pathological conditions such as rubeosis iridis and iris racemose hemangiomas [31,32]. Skalet and colleagues evaluated melanocytic iris tumors suggesting an increased iris vascularity as a hall-mark of malignant transformation [33].…”

Section: Discussionmentioning

confidence: 99%

Changes in Iris Perfusion Following Scleral Buckle Surgery for Rhegmatogenous Retinal Detachment: An Anterior Segment Optical Coherence Tomography Angiography (AS-OCTA) Study

D’Aloisio

Viggiano

Borrelli

et al. 2020

JCM

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Purpose: To investigate iris vasculature changes following scleral buckling (SB) surgery in eyes with rhegmatogenous retinal detachment (RRD) with anterior-segment (AS) optical coherence tomography angiography (OCTA). Methods: In this prospective study, enrolled subjects were imaged with an SS-OCTA system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). Image acquisition of the iris was obtained using an AS lens and a manual focusing adjustment in the iris using the retina imaging software. The quantitative analysis was performed in eight different iris regions: (i) superior, (ii) supero-temporal, (iii) supero-nasal, (iv) nasal, (v) temporal, (vi) inferior, (vii) infero-temporal, (viii) infero nasal which, were defined as squares with area of 1.5 mm2. Results: Fifteen eyes of 15 patients (six females; nine males) were included. Anterior segment optical coherence tomography angiography (AS-OCTA) parameters of the iris were statistically compared at baseline (preoperatively), 1 week, 1 month and 6 months after SB. At post-operative 1 week, perfusion density (PD) showed a significant decrease from 66.8 ± 13.2% to 58.55 ± 12.0% in the iris supero-nasal region (p = 0.016). However, at the 1-month follow-up visit, iris PD was significantly lower in all the analyzed iris regions, apart from the superior one. Conclusions: This study is the first description of AS-OCTA in patients undergoing SB. Our results showed a uniform reduction of the iris vessel network at 1 month after surgery, supporting the clinical use of AS-OCTA to identify early iris perfusion changes as potential predictive biomarkers of vascular disorders.

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Optical Coherence Tomography Angiography Features of Iris Racemose Hemangioma in 4 Cases

Cited by 28 publications

References 13 publications

Optical coherence tomography angiography (OCTA) applications in ocular oncology

Optical coherence tomography angiography (OCTA) applications in ocular oncology

Quantitative analysis of conjunctival microvasculature imaged using optical coherence tomography angiography

Changes in Iris Perfusion Following Scleral Buckle Surgery for Rhegmatogenous Retinal Detachment: An Anterior Segment Optical Coherence Tomography Angiography (AS-OCTA) Study

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