“… Outcome | Studies | No. of Patients | Results |
Survival with favorable neurological outcome | 1 cluster RCT, 150 low-certainty evidence (downgraded for very serious risk of bias) 4 observational, 151 , 152 , 153 , 154 very-low-certainty evidence (downgraded for very serious risk of bias) | 1586 | No difference: Relative risk 1.02; 95% CI, 0.76–1.36; P = 0.9 Absolute risk 0.19% (95% CI, −3.18% to 2.82%), or 2 more patients/1000 survived with the intervention (95% CI, 24 fewer patients/1000 to 36 more patients/1000 survived with the intervention) Better outcome with feedback: Adjusted odds ratio 2.69 (95% CI, 1.04–6.94) 153 |
1100 | No difference:Adjusted relative risk 5.75%; 95% CI, -18.51% to 3.85%152Adjusted odds ratio 0.92; 95% CI, 0.37–2.301512/16 versus 0/16; P=0.14154 |
Survival to hospital discharge | 1 cluster RCT,150low-certainty evidence (downgraded for very serious risk of bias) 6 observational: 5 in adults 127 , 131 , 151 , 153 , 155 and 1 in children, 156 very-low-certainty evidence (downgraded for very serious risk of bias) | 1586 | No difference: |
| Relative risk: 0.91 (95% CI, 0.69–1.19); P?=?0.5Absolute risk: -1.16% (95% CI, -4.37% to 2.02%), or 9 fewer patients/1000 survived with the intervention (95% CI, 31 fewer patients/1000 to 19 more patients/1000 survived with the intervention) |
1592 | No difference: |
| Adjusted odds ratio 0.90; 95% CI, 0.39–2.06; P?=?0.80),151Adjusted relative risk -0.91; 95% CI, -11.18 to 12.33),152Adjusted relative risk 5.23; 95% CI, -0.49 to 10.89),153Adjusted relative risk -0.18; 95% CI, -11.46 to 8.64),155Adjusted relative risk 1.37; 95% CI, -2.47 to 6.91),1318 children (ages 1–7 yr) with IHCA (1/4 versus 1/4)156 |
Survival to 30 days | 1 observational, 157 very-low-certainty evidence (downgraded for seriou... |
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