289 Long-Term Follow-up After Anti-Reflux Surgery in Patients With Barrett's Esophagus

Zehetner, Joerg; DeMeester, Steven R.; Ayazi, Shahin; Costales, Jesse L.; Augustin, Florian; Sohn, Helen J.; Lipham, John C.; Hagen, Jeffrey A.; DeMeester, Tom R.

doi:10.1016/s0016-5085(10)63907-8

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Evidence For Prevention Of Progression With Antireflux Surgery1

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2021

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“…The rates of progression in this study were comparable to the ones in a similar study by Zehetner et al. 32 The results of these studies on surgical treatment regarding regression and progression are summarized in Table 1.…”

Section: Evidence For Prevention Of Progression With Antireflux Surgerysupporting

confidence: 87%

Cancer Prevention in Patients with GERD and Barrett’s Esophagus: Surgery

Oelschlager

Ceron

2021

Foregut

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Barrett’s esophagus (BE) is an acquired pre-malignant condition that is the result of chronic damage to the esophagus mucosa caused by reflux. Gastroesophageal reflux disease (GERD) and BE are major risks factors for esophageal adenocarcinoma. Effective treatment for BE should control GERD symptoms but these patients frequently presents with other associated conditions that makes management more challenging. Laparoscopic antireflux surgery (LARS), restoring the gastroesophageal barrier, is a very effective treatment of patients with BE, but its role in cancer prevention remain controversial. There is strong evidence that surgery can promote regression, but less so for reducing progression. The aim of this article was to review the current role of antireflux surgery in preventing progression to dysplasia or cancer in patients with BE and GERD.

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Section: Evidence For Prevention Of Progression With Antireflux Surgerysupporting

confidence: 87%