“Click” reaction based synthesis of nimbolide derivatives and study of their insect antifeedant activity against Spodoptera litura Larvae

UPLC-MSE Guided Isolation of New Antifeedant Limonoids from Fruits of Trichilia connaroides

“…During the past decade, our group has focused on phytochemical investigations of medicinal plants of the Meliaceae family, resulting in a series of structurally intriguing limonoids with potential biological activities including antifeedant activities. − Recently, we have reported the isolation and characterization of two new seco phragmalin-type limonoids from the CHCl 3 extract from fruits of T. connaroides . In continuation of our efforts to identify new limonoids from Trichilia species, we performed the LC-MS E analysis of chloroform extract from T. connaroides by UPLC-Q-TOF-MS/MS technique, which clearly demonstrated the existence of new limonoids in minor quantities (Figure ).…”