A comparison of the effects of copper nanoparticles and copper sulfate on Phaeodactylum tricornutum physiology and transcription

Nanoparticle Exposure and Hormetic Dose–Responses: An Update

“…The hormetic phenomenon described by Zhu et al [ 23 ] was also confirmed by the results obtained with Cu nano-aquachelates carboxylated with citric acid on the biomass accumulation of the green algae Chlorella vulgaris [ 24 ]. This latter finding may be dependent on the increase in inorganic copper concentration which may impair biochemical and physiological processes in algal cells.…”

“…Copper nanoparticles (Cu-NPs) have found application in a large range of production fields, including printing, lithium ion battery production, and biomaterial synthesis and are potentially released from industrial sewage into the aquatic environment [ 45 ]. Concerning possible hormetic effects on aquatic ecosystems, the exposure of marine diatom P. tricornutum to low concentrations of Cu-NPs showed a slight growth stimulation, while the treatment with higher concentrations induced a significant inhibition of the growth rate [ 23 ]. However, these results are quite different compared to those previously obtained by Morelli et al [ 46 ] who demonstrated that CdSe/ZnS quantum dots did not exert a biphasic response in the same marine diatom.…”

“…For example, stimulatory action of Ag-NPs was greater for NP formulations with a smaller diameter in human cell [ 12 ], plant [ 26 ] and larval models [ 34 ], than for NPs with a greater size [ 13 ]. Therefore, it can be speculated that factors other than size, including the original state of the material, e.g., powder vs. colloidal dispersion [ 12 ], the NP chemical composition [ 14 , 16 , 23 , 24 ] ( Figure 4 ), the agglomeration status [ 12 ], and ENM surface functionalization [ 13 , 16 , 26 ] ( Figure 4 ), should be considered as possible key factors in the hormetic response to NP insults.…”

Interaction of Copper-Based Nanoparticles to Soil, Terrestrial, and Aquatic Systems: Critical Review of the State of the Science and Future Perspectives

“…In addition, several studies highlighted toxicity of Cu-based NPs on aquatic organisms including gill injury and acute lethality in zebrafish and toxicity to algal species (Aruoja et al 2009;Griffitt et al 2007;Griffitt et al 2009), induction of oxidative stress in the liver, gills and muscles of juvenile Epinephelus coioides (Wang et al 2014) and in mussels (Gomes et al, 2014) Similarly, Giannetto et al (2018) found that CuO-NPs affected oxidative stress-related genes of Arbacia lixula embryos. A short-term study on diatom showed that Cu-NPs inhibited the growth, photosynthesis and induced oxidative stress on Phacodactylum tricornutum (Zhu et al 2017). Three different Lemnaceae species (Spirodela polyrhiza, Lemna minor and Wolffia arrhiza) commonly found in freshwater lakes exposed to Cu-NPs expressed different sensitivities (Song et al 2015a).…”

Interaction of zero valent copper nanoparticles with algal cells under simulated natural conditions: Particle dissolution kinetics, uptake and heteroaggregation

“…As a consequence of their high production and use, these ENPs (and metal ENPs in general) may be released to the environment and affect the ecosystems, mainly aquatic systems and sediments (Peijnenburg et al, 2015;Wiesner et al, 2006). Currently, there are many studies focusing on studying the physicochemical behaviour and fate of Cu ENPs and/or their toxicity in different organisms (Dobrochna et al, 2018;Griffitt et al, 2007;Pu et al, 2016;Sharma et al, 2015;Song et al, 2015;Wang et al, 2014;Xiao et al, 2018;Zhu et al, 2017), although more studies focused specifically on the effects of the different physicochemical water properties are needed to understand the toxicity effects of Cu ENPs. As it is known, dissolution and aggregation of ENPs can both be affected by physicochemical parameters of aquatic systems, such as pH, ionic strength and natural organic matter (NOM) (Keller et al, 2010;Li et al, 2012Li et al, , 2010, and also by the physicochemical properties of the ENPs, such as size, shape and chemical composition (Cornelis et al, 2014;Lead et al, 2018;Lowry et al, 2010).…”