Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk

Abstract

Bovine mastitis a major disease that is commonly associated with bacterial infection. The common treatment is with antibiotics administered intramammary into infected quarters of the udder. The excessive use of antibiotics leads to multidrug resistance and associated risks for human health. In this context, the search for alternative drugs based on plants has become a priority in livestock medicine. These products have a low manufacturing cost and no reports of antimicrobial resistance to these have been documented. In this context, the main objective of this study was to determine the antimicrobial effect of extracts and products of several indigenous, or acclimatized plants on pathogens isolated from bovine mastitis. A total of eleven plant alcoholic extracts and eight plant-derived products were tested against 32 microorganisms isolated from milk. The obtained results have shown an inhibition of bacterial growth for all tested plants, with better results for Evernia prunastri, Artemisia absinthium, and Lavandula angustifolia. Moreover, E. prunastri, Populus nigra, and L. angustifolia presented small averages of minimum inhibitory and bactericidal concentrations. Among the plant-derived products, three out of eight have shown a strong anti-microbial effect comparable with the effect of florfenicol and enrofloxacin, and better than individual plant extracts possibly due to synergism. These results suggest an important anti-microbial effect of these products on pathogens isolated from bovine mastitis with a possible applicability in this disease.

Antimicrobial and Antiproliferative Activities of Vincetoxicum canescens subsp. canescens and Vincetoxicum cancescens subsp. pedunculata Seeds

“…Geleneksel kullanımları, fitokimyasal bileşimleri ve farmakolojik etkileri nedeniyle bitkiler uzun zamandır dikkatleri üzerine çekmektedir. 1 Literatürde bitkilerin tedavi edici etkilerini gösteren çok sayıda çalışma olup; 20.000'den fazla tıbbi bitkinin zatürre, diyare, ülser, soğuk algınlığı, bronşit ve solunum yolu hastalıkları gibi çeşitli hastalıkların tedavisinde kullanıldığı Dünya Sağlık Örgütü tarafından bildirilmiştir. 2 Kendilerine karşı kullanılan antimikrobiyal ilaçlara karşı mikroorganizmaların direnç geliştirme potansiyelleri bulunmaktadır.…”

Needles of Abies Sibirica in the Treatment of Subclinical Mastitis in Cows

“…Whole plants or parts thereof are used to prepare different medications (Balakrishnan et al, 2017;Rastogi et al, 2015). Studies confirm that plants and plant-based medications have an inhibitory and antimicrobial effect on MC agents (Pașca et al, 2017). Therefore, the use of medicinal plants implies a promising perspective for the treatment of MC.…”

Garlic (Allium sativum L.) as an antibiotic alternative determining the hygienic quality of cow’s milk from organic farms

“…Hashemzadeh-Cigari et al (2014) have showed improved feed intake, performance, udder health, ruminal fermentation, and plasma metabolites in cows with moderate or high SCC in the milk due to their diet supplementation with a phytobiotics-rich herbal mixture. In turn, an experiment performed by Pasca et al (2017) to test the inhibitory effect of phytobiotics obtained from several plant species has shown a stronger antimicrobial activity of the coupled use of the phytobiotics compared to the individual application of each plant-based products. In the literature available, not many researchers deal with the influence of garlic on mastitis prevention, especially at organic farms.…”