Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials

Abstract

Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare. This guidance has 3 overarching aims: ) protecting the welfare of research animals;) according fair treatment and due process to an individual accused of noncompliance; and ) ensuring compliance with federal regulations. Through this guidance, the present work seeks to advance the cause of scientific integrity, animal welfare, and the public trust while recognizing and supporting the critical importance of animal research for the betterment of the health of both humans and animals.-Hansen, B. C., Gografe, S., Pritt, S., Jen, K.-L. C., McWhirter, C. A., Barman, S. M., Comuzzie, A., Greene, M., McNulty, J. A., Michele, D. E., Moaddab, N., Nelson, R. J., Norris, K., Uray, K. D., Banks, R., Westlund, K. N., Yates, B. J., Silverman, J., Hansen, K. D., Redman, B. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials.

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“…Prior to beginning work, all institutions that perform research with laboratory animals are required to have an Institutional Animal Care and Use Committee (IACUC)-approved protocol (Silverman et al, 2017, Silverman, 2017, Hansen et al, 2017). Likewise, all institutions performing research of any type involving human subjects are required to have an Institutional Review Board (IRB)-approved protocol, the key component differentiating the latter from the former being the informed consent process, which attempts to assure subjects’ right to choose participation in a given study on the basis of the risks and benefits as presented by the researchers (Kane & Gallo, 2017, Goldenberg et al, 2015).…”