A new index to simplify the screening of hypertension in overweight or obese youth

Bonito, Procolo Di; Valerio, Giuliana; Pacifico, Lucia; Chiesa, Claudio; Invitti, Cecilia; Morandi, Anita; Maffeis, Claudio; Licenziati, Maria Rosaria; Manco, Melania; Giudice, Emanuele Miraglia del; Baroni, Marco Giorgio; Loche, Sandro; Tornese, Gianluca; Tomat, M.; Simone, Giuseppina De; Gilardini, Luisa; Sanguigno, Eduardo; Franco, Francesca; Grandone, Anna; Luciano, Rosa; Incani, Michela; Pellegrin, Maria Chiara

doi:10.1016/j.numecd.2017.06.013

Cited by 7 publications

(3 citation statements)

References 32 publications

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“…Second, blood pressure was measured only on a single day, while hypertension confirmation requires three blood-pressure measurements on separate days. However, it is somewhat impractical to measure blood pressure in triplicate on different days in a large-scale epidemiological study [ 30 ]. Finally, although our sensitivity analysis suggests that the presence of anemia did not significantly influence the performance of HbA 1c , other conditions, including hemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency, may affect the relationship between HbA 1c and diabetes detection [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Exploration and Validation of the Performance of Hemoglobin A1c in Detecting Diabetes in Community-Dwellers With Hypertension

Qiu

et al. 2020

Ann Lab Med

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Background Diabetes can complicate hypertension management by increasing the risk of cardiovascular disease (CVD) and all-cause mortality. Studies targeting diabetes detection in hypertensive individuals demonstrating an increased risk of diabetes are lacking. We aimed to assess the performance of hemoglobin A 1c (HbA 1c ) and its cut-off point in detecting diabetes in the abovementioned population. Methods Data from 4,096 community-dwellers with hypertension but without known diabetes were obtained from the Study on Evaluation of iNnovated Screening tools and determInation of optimal diagnostic cut-off points for type 2 diaBetes in Chinese muLti-Ethnic (SENSIBLE) study; these data were randomly split into exploration (70% of the sample) and internal validation (the remaining 30%) datasets. The optimal HbA 1c cut-off point was derived from the exploration dataset and externally validated using another dataset from 2,431 hypertensive individuals. The oral glucose tolerance test was considered the gold-standard for confirming diabetes. Results The areas under the ROC curves for HbA 1c to detect diabetes were 0.842, 0.832, and 0.829 for the exploration, internal validation, and external validation datasets, respectively. An optimal HbA 1c cut-off point of 5.8% (40 mmol/mol) yielded a sensitivity of 76.2% and a specificity of 74.5%. Individuals who were not diagnosed as having diabetes by HbA 1c at 5.8% (40 mmol/mol) had a lower 10-year CVD risk score than those diagnosed as having diabetes ( P =0.01). HbA 1c ≤5.1% (32 mmol/mol) and ≥6.4% (46 mmol/mol) could indicate the absence and presence of diabetes, respectively. Conclusions HbA 1c could detect diabetes effectively in community-dwellers with hypertension.

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Section: Discussionmentioning

confidence: 99%

Exploration and Validation of the Performance of Hemoglobin A1c in Detecting Diabetes in Community-Dwellers With Hypertension

Qiu

et al. 2020

Ann Lab Med

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“…These conditions led to an alarming underdiagnosis of pediatric HTN. According to a previous investigation, approximately 70% of clinicians and specialists only assessed pediatric BP when the children exhibited signs or symptoms of HTN, and 65% of them compared the results of measurements by various guidelines (14).…”

Section: Screening Of Htn In Children and Adolescentsmentioning

confidence: 99%

The importance of screening for hypertension in children and adolescents

et al. 2023

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Hypertension (HTN) is the most prevalent chronic non-infected disease and the greatest cause of adult premature mortality. Although in the past clinicians assumed that HTN in childhood and adolescents is uncommon, it is currently a significant public health issue and this narrative review aimed to assess the new finding regarding screening for HTN in Children and adolescents. Relevant English publications were extracted from Web of Science, PubMed, Scopus, and Google Scholar. As there are gaps regarding recommendations, guidelines, and screening for HTN in children and adolescents, this review tried to notice some important points.

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“…One of the aids is the above mentioned BMI. Today, some other efficient tools to identify childhood hypertension are the blood pressure-to-height index (BPHi) [7] and the height-specific blood pressure threshold (HBP) [8]. But there is an other aspect of height and blood pressure (BP) ratio.…”

Section: The Problematics Of the Height And Blood Pressure (Bp) Relationshipmentioning

confidence: 99%

Approximations and Indexes in the Medicine: the BMI and the BPHi

Télessy

2018

BJSTR

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A new index to simplify the screening of hypertension in overweight or obese youth

Cited by 7 publications

References 32 publications

Exploration and Validation of the Performance of Hemoglobin A1c in Detecting Diabetes in Community-Dwellers With Hypertension

Exploration and Validation of the Performance of Hemoglobin A1c in Detecting Diabetes in Community-Dwellers With Hypertension

The importance of screening for hypertension in children and adolescents

Approximations and Indexes in the Medicine: the BMI and the BPHi

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