When Gender Identity Doesn't Equal Sex Recorded at Birth: The Role of the Laboratory in Providing Effective Healthcare to the Transgender Community

Goldstein, Zil; Corneil, Trevor; Greene, Dina N.

doi:10.1373/clinchem.2016.258780

Cited by 67 publications

(49 citation statements)

References 53 publications

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“…Additionally, laboratory tests should be ordered based on biological sex (eg, prostate specific antigen [PSA] for transgender female, human chorionic gonadotropin [hCG] for transgender male). 39,45 For transgender patients who receive hormones and/or testosterone blockers, alterations in laboratory values may be present that are related to the pharmacology of the replacement therapies. Hormone replacement therapies can influence many hematologic, general chemistry, and special chemistry/endocrine values (Table 5).…”

Section: Preoperative Carementioning

confidence: 99%

“…Hormone replacement therapies can influence many hematologic, general chemistry, and special chemistry/endocrine values (Table 5). 45 These changes to laboratory results are highly variable in terms of an increase, decrease, or no change as cited by Goldstein et al 45 When interpreting values for transgender patients receiving hormones, it is important to consider the physiology behind each test and whether the male or female range is more appropriate. It has been suggested that transitioning transgender patients on hormone replacement therapy for >6 months should have their laboratory values compared to that of their cis-counterparts and not their sex assigned at birth 45 However, limited evidence is available to guide the evaluation of laboratory test interpretation in the different stages of transition.…”

Section: Preoperative Carementioning

confidence: 99%

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The Perioperative Care of the Transgender Patient

Tollinche

Walters

Radix

et al. 2018

Anesthesia &Amp; Analgesia

123

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An estimated 25 million people identify as transgender worldwide, approximately 1 million of whom reside in the United States. The increasing visibility and acceptance of transgender people makes it likely that they will present in general surgical settings; therefore, perioperative health care providers must develop the knowledge and skills requisite for the safe management of transgender patients in the perioperative setting. Extant guidelines, such as those published by the World Professional Association for Transgender Health and the University of California San Francisco Center of Excellence for Transgender Health, serve as critical resources to those caring for transgender patients; however, they do not address their unique perioperative needs. It is essential that anesthesia providers develop the knowledge and skills necessary for safely managing transgender patients in the perioperative setting. This review provides an overview of relevant terminology, the imperative for the provision of culturally sensitive care, and guidelines for preoperative, intraoperative, and postoperative management of the transgender patient.

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Section: Preoperative Carementioning

confidence: 99%

Section: Preoperative Carementioning

confidence: 99%

The Perioperative Care of the Transgender Patient

Tollinche

Walters

Radix

et al. 2018

Anesthesia &Amp; Analgesia

123

View full text Add to dashboard Cite

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“…Unfortunately, the ways these values may change are not always consistent or predictable. Studies in adult populations have demonstrated a variety of findings, with the same laboratory values increasing, decreasing, or not significantly changing among different studies 34,35,39 (Table 4).…”

Section: Anesthesia and Perioperative Issuesmentioning

confidence: 99%

Transgender pediatric surgical patients—Important perioperative considerations

Roque

2020

Pediatric Anesthesia

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Transgender describes a variety of identities in which an individual's gender identity is different from expected based on the sex assigned at birth. In the United States, it is estimated that over 1 million adults and 150 000 youth identify as transgender, with increasing numbers being seen in healthcare and surgical settings. These numbers will continue to rise as visibility and acceptance grow. Current guidelines recommend transition‐related surgeries be reserved for older adolescents and adults. However, this is not the only circumstance in which the pediatric anesthesiologist may find themselves caring for a transgender patient. In order to provide the safest and most affirming care, it is crucial that the pediatric anesthesiologist develop a working knowledge of this unique and vulnerable population, including the potential impacts of gender‐affirming treatment on their perioperative care.

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“…Other areas of pathology are also impacted by sex/gender incongruence . For example, receiving orders for pregnancy testing on male patients can lead to cancellation within some laboratory information systems.…”

mentioning

confidence: 99%

“…Other areas of pathology are also impacted by sex/ gender incongruence. 8 For example, receiving orders for pregnancy testing on male patients can lead to cancellation within some laboratory information systems. Additionally, tissue biopsies received from sex-specific anatomic locations, such as the cervix or prostate, may cause confusion when the tissue is logged into electronic systems.…”

mentioning

confidence: 99%