Effect of Percutaneous Edge-to-Edge Repair on Mitral Valve Area and Its Association With Pulmonary Hypertension and Outcomes

Role of the learning curve in very high–risk patients treated with MitraClip device for functional mitral regurgitation: a single-centre experience

“…This finding is in line with the report by Boerlage-van Dijk et al [10], who also noticed a significantly higher gradient in daily life after the procedure than during MitraClip implantation. Importantly, several authors found that higher post-procedural mitral gradients are linked to worse clinical outcome [11,12]. According to our data, the mitral valve gradient was not affected by the learning curve.…”

Myocardial fibrosis and MitraClip: Does it even matter?

“…Apart from the cause of MR, acute postprocedural variables also affect long‐term outcomes. For example, a transvalvular gradient >5 mmHg or a calculated mitral valve area <1.94 cm 2 correlates with a smaller decrease in pulmonary artery pressure over time and, consequently, worse overall prognosis. Given the current advances in transcatheter mitral valve technology, it is important to better risk‐stratify patients, even before they undergo the procedure, to better inform them about the risks and to better manage them postoperatively.…”

Different indicators for postprocedural mitral stenosis caused by single- or multiple-clip implantation after percutaneous mitral valve repair

“…The mean TMPG using continuous-wave (CW) Doppler is often used as a parameter to assess the postprocedural mitral stenosis (MS) after MitraClip implantation because it is easy to apply in the catheterization laboratory [4][5][6]. Of preprocedural mitral parameters, small preprocedural MVOA and mitral annular size are considered to be associated with the high postprocedural mean TMPG in the previous papers [7][8][9][10][11][12][13][14][15][16][17][18].…”