Sorption of thiabendazole in sub-tropical Brazilian soils

Abstract

Thiabendazole (TBZ) is an ionizable anthelmintic agent that belongs to the class of benzimidazoles. It is widely used in veterinary medicine and as a fungicide in agriculture. Sorption and desorption are important processes influencing transport, transformation, and bioavailability of xenobiotic compounds in soils; data related to sorption capacity are therefore needed for environmental risk assessments. The aim of this work was to assess the sorption potential of TBZ in four Brazilians soils (sandy, sandy-clay, and clay soils), using batch equilibrium experiments at three pH ranges (2.3-3.0, 3.8-4.2, and 5.5-5.7). The Freundlich sorption coefficient (K ) ranged from 9.0 to 58 μg (mL) g, with higher values generally observed at the lower pH ranges (2.3-3.0 and 3.8-4.2) and for clay soils. The highest organic carbon-normalized sorption coefficients (K) obtained at pH 3.8-5.7 (around the natural pH range of 4.1-5.0) for both clay soils and sandy-clay soil were 3255 and 2015 mL g, respectively. The highest correlations K vs SOM (r = 0.70) and K vs clay content (r = 0.91) were observed at pH 3.8-4.2. Our results suggest that TBZ sorption/desorption is strongly pH dependent and that its mobility could be higher in the studied soils than previously reported in soils from temperate regions.

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

“…It was detected in biological waste samples in concentrations of up to 600 μg/kg [ 63 ]. A third source of environmental BZs might be runoff from livestock farms because they are used extensively to prevent parasite infections in these animals [ 60 – 62 , 64 ]. The observation that putative ben-1 loss-of-function alleles are only found at low frequencies in the C .…”

Kinetic and equilibrium adsorption of two post-harvest fungicides onto copper-exchanged montmorillonite: synergic and antagonistic effects of both fungicides’ presence

“…IMZ is considered Blikely to be carcinogen in humans^by USA Environmental Protection Agency (Environmental Protection Agency (EPA) n.d.-a), while TBZ shows generally low acute toxicity in humans but high toxicity to freshwater estuarine fish and freshwater/estuarine invertebrates (Environmental Protection Agency (EPA) n.d.-b). Thiabendazole has been detected in surface waters and sediment compartments (de Oliveira Neto OF et al 2017).…”

Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 3. Fixed‐dose study of imazalil

“…Pascual Aguilar, Andreu, Campo, Picó, and Masiá (2017) reported that a high concentration of IMZ (222.45 ng/L) was detected in surface water in Spain. TBZ has been detected in surface water and sediment compartments in the sub‐tropical area of Brazil (de Oliveira Neto, Arenas, & Fostier, 2017). Fonseca et al (2019) reported that the most detected compounds in surface water were herbicides and fungicides (including IMZ and TBZ) in Spain.…”