Analgesic effect of intraperitoneal local anesthetic in surgery: an overview of systematic reviews

Hamill, James; Rahiri, Jamie‐Lee; Hill, Andrew

doi:10.1016/j.jss.2017.01.022

Cited by 22 publications

(16 citation statements)

References 43 publications

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“…Intraperitoneal local anaesthetic use has been gaining recent interest with two recent systematic reviews published within the last year demonstrating positive analgesic effects in laparoscopic cholecystectomy, gynaecological and gastric surgeries . Our study has confirmed the early analgesic effects of intraperitoneal local ropivacaine in laparoscopic appendicectomy in an Australian population during the first 6‐h post operation.…”

Section: Discussionsupporting

confidence: 75%

“…The exact aetiology of pain after laparoscopic surgery is still unclear, but it does appear to be multifactorial; causes include abdominal wall trauma from trocar insertion, diaphragmatic irritation by insufflated gas and chemical or blood irritation of the peritoneum . The peritoneum is a continuous sheet of mesothelial cells that is richly innervated on both the parietal and visceral surfaces, which may have an important role in the direct analgesic effect by local anaesthetics . Some studies have demonstrated that after a bolus of intraperitoneal local anaesthetic administration, local anaesthetic levels can be detected in the systemic system within 2–4 min, with rapid absorption.…”

Section: Introductionmentioning

confidence: 99%

“…Currently, intraoperative use of local anaesthetic is not routinely given in laparoscopic appendicectomies. Although its use has been widely studied in laparoscopic hernia repairs, gynaecological laparoscopy and laparoscopic cholecystectomies, no Australian study investigating its role in laparoscopic appendicectomy has been published. There is some recent evidence from overseas studies from Malaysia and Korea to suggest ropivacaine is safe and works well as an analgesic agent when given intraperitoneally, while others have used other agents such as lornoxicam, bupivacaine and tramadol instead of ropivacaine .…”

Section: Introductionmentioning

confidence: 99%

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The role of intraperitoneal ropivacaine in laparoscopic appendicectomy: a prospective, double‐blinded randomized control Australian study

Huang¹,

Suthananthan²,

Hunt³

et al. 2019

ANZ Journal of Surgery

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Background: Currently, intraoperative use of local anaesthetic is not routinely given in all laparoscopic appendicectomies. Although its use has been widely studied in laparoscopic hernia repairs, gynaecological laparoscopy and laparoscopic cholecystectomies, there are no published trials of the use of intraperitoneal local anaesthetic during laparoscopic appendicectomy in the Australasian setting. The aim of this study was to determine whether the use of intraperitoneal ropivacaine during laparoscopic appendicectomy will reduce the amount of post-operative opiate analgesia used, abdominal pain, post-operative nausea or vomiting, shoulder tip pain and length of hospital stay. Methods: A randomized double-blinded placebo versus control trial was conducted with patients with clinically diagnosed appendicitis undergoing laparoscopic appendicectomy. Primary outcomes measured were the number of times the patient-controlled analgesia (PCA) button was pressed post-operatively and the average and total amount of fentanyl from PCA consumed during the post-operative period from 0 to 6 h and from 6 to 16 h. Results: A total of 86 patients with 43 patients in the placebo normal saline group and 43 patients in the treatment ropivacaine group were included in the study. During the immediate post-operative period (0-6 h), there was a statistically significant reduction in the number of times the PCA button was pressed in the ropivacaine group compared to the normal saline group (16 versus 24 times, P = 0.02). Conclusion: Intraperitoneal ropivacaine has an analgesic effect for patients up to 6 h following emergency laparoscopic appendicectomy.

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Section: Discussionsupporting

confidence: 75%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The role of intraperitoneal ropivacaine in laparoscopic appendicectomy: a prospective, double‐blinded randomized control Australian study

Huang¹,

Suthananthan²,

Hunt³

et al. 2019

ANZ Journal of Surgery

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“…A administração de anestesia local oferece vários benefícios ao sistema de saúde, incluindo maior satisfação do paciente, alta hospitalar precoce e redução na admissão hospitalar não planejada [2][3][4][5] . Por isso, a pergunta de pesquisa desse trabalho é "quais são os elementos essenciais para a realização de anestesia local consciente por um profissional da área da saúde?".…”

Section: Introductionunclassified

Anestésicos e anestesia locais: revisão narrativa de literatura para a prática clínica

Fleury

Corte

Costa

et al. 2021

Com. Ciências Saúde

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Objetivo: revisar a literatura sobre elementos-chave para a utilização correta dos anestésicos locais. Método: revisão narrativa de 41 trabalhos disponíveis na bases de dados Medline/PubMed, BIREME e publicações da Sociedade Brasileira de Anestesiologia (SBA). Resultados: foram descritos os mecanismos de ação, a farmacocinética, a farmacodinâmica, as doses máximas, a técnica de diluição, as situações de alerta e as condutas frente à suspeita de intoxicação. Também foram descritas as particularidades de grupos como neonatos, gestantes e idosos. Conclusão: os resultados deste estudo compõe o acervo de conhecimento que tornam o profissional mais capacitado para o uso do anestésico local.

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“…These drugs are inexpensive, not scheduled, and are readily available world-wide. Intraperitoneal (IP) administration of local anaesthetics reduces early postoperative analgesic requirements, time to first-intervention analgesia and pain scores after abdominal surgery in humans; it is currently recommended for laparoscopic surgery as an adjuvant analgesic technique (Boddy et al 2006, Kahokehr et al 2011, Hamill et al 2017. Based on these results in the human literature, the WSAVA-GPC (Monteiro et al 2019) guidelines recommended IP and incisional analgesia for the management of pain, particularly as adjuvant techniques for pain relief in dogs and cats undergoing abdominal surgery (Mathews et al 2014).…”

mentioning

confidence: 99%

Intraperitoneal and incisional analgesia in small animals: simple, cost‐effective techniques

Steagall

Benito

Monteiro

et al. 2019

J of Small Animal Practice

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The World Small Animal Veterinary Association Global Pain Council (WSAVA‐GPC) has recently published its first “capsule review” by Monteiro et al. These are short articles that present a brief assessment of the scientific evidence and practical recommendations on important, and sometimes controversial, subjects in pain management. The capsules will be published regularly in the Journal of Small Animal Practice, the official journal of the WSAVA. This second article discusses the use of intraperitoneal and incisional analgesia in small animal practice, including their limitations and recommendations by the authors.

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Analgesic effect of intraperitoneal local anesthetic in surgery: an overview of systematic reviews

Cited by 22 publications

References 43 publications

The role of intraperitoneal ropivacaine in laparoscopic appendicectomy: a prospective, double‐blinded randomized control Australian study

The role of intraperitoneal ropivacaine in laparoscopic appendicectomy: a prospective, double‐blinded randomized control Australian study

Anestésicos e anestesia locais: revisão narrativa de literatura para a prática clínica

Intraperitoneal and incisional analgesia in small animals: simple, cost‐effective techniques

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