Influence of bladder lithiasis on lower urinary tract dynamics in patients with spinal cord injury

Purpose of review This review aims to update the studies involving the treatment of lower urinary tract symptoms (LUTS) in neurogenic patients, published in the last two years. Recent findings Treatment of neurogenic LUTS (NLUTS) patients with β3 adrenoreceptor agonists was investigated in real-life conditions. A randomized controlled trial compared the efficacy of antimuscarinics versus onabotulinum toxin A in neurogenic patients. The use of desmopressin to treat nocturia in multiple sclerosis patients is also reported. The long-term treatment with BontA efficacy, its discontinuation, and possible strategies to maintain patients on treatment were also evaluated. Sacral neuromodulation and tibial nerve stimulation are continuously being evaluated in neurogenic patients, especially in the last years. Summary The management of urinary tract infections and vesical lithiasis, two common complications in NLUTS patients, and the management of both these patients was assessed in clinical trials. A trial evaluating the use of the anti-Nogo-A antibody after a spinal cord injury to facilitate neuronal rewiring and prevent or improve NLUTS was reported for the first time.

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Treatment of neurogenic lower urinary tract symptoms: main contributions from 2018 and 2019

Abreu-Mendes¹,

Cruz

Martins-Silva

2020

Current Opinion in Urology

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Influence of bladder lithiasis on lower urinary tract dynamics in patients with spinal cord injury

Abstract: Bladder lithiasis affects the presence of NDO in patients with SCI. Patients with SCI who develop bladder lithiasis present a lower detrusor contractility power compared with those who do not.

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References 16 publications

Treatment of neurogenic lower urinary tract symptoms: main contributions from 2018 and 2019

Treatment of neurogenic lower urinary tract symptoms: main contributions from 2018 and 2019

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