Vascular complications associated with transcatheter aortic valve replacement

Sardar, Muhammad; Goldsweig, Andrew M.; Abbott, J. Dawn; Sharaf, Barry L.; Gordon, Paul; Ehsan, Afshin; Aronow, Herbert D.

doi:10.1177/1358863x17697832

Cited by 33 publications

(20 citation statements)

References 92 publications

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“…It is routine clinical practice to obtain preoperative imaging for the assessment of femoral artery calcification and diameter, both of which are independent predictors of vascular complications in patients undergoing transfemoral TAVR. Furthermore, vascular complications are significantly associated with periprocedural morbidity and mortality . However, real‐world estimates of PAD prevalence and the association of PAD with in‐hospital outcomes in patients undergoing TAVR are limited.…”

Section: Introductionmentioning

confidence: 99%

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Association of peripheral artery disease with in‐hospital outcomes after endovascular transcatheter aortic valve replacement

Mohananey

Villablanca

Gupta

et al. 2019

Cathet Cardio Intervent

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Objectives The aim of this study was to determine the prevalence of peripheral artery disease (PAD) and its association with in‐hospital outcomes after endovascular transcatheter aortic valve replacement (EV‐TAVR). Background TAVR is an established treatment for patients at prohibitive, high, or intermediate surgical risk. PAD is a significant comorbidity in the determination of surgical risk. However, data on association of PAD with outcomes after EV‐TAVR are limited. Methods Patients in the National Inpatient Sample who underwent EV‐TAVR between January 1, 2012 and September 30, 2015 were evaluated. The primary outcome was in‐hospital mortality. Results A total of 51,685 patients underwent EV‐TAVR during the study period. Of these, 12,740 (24.6%) had a coexisting diagnosis of PAD. The adjusted odds for in‐hospital mortality [OR 1.08 (95% CI 0.83–1.41)], permanent pacemaker implantation [OR 0.98 (0.85–1.14)], conversion to open aortic valve replacement [OR 1.05 (0.49–2.26)], or acute myocardial infarction [OR 1.31(0.99–1.71)] were not different in patients with versus without PAD. However, patients with PAD had greater adjusted odds of vascular complications [OR 1.80 (1.50–2.16)], major bleeding [OR 1.20 (1.09–1.34)], acute kidney injury (AKI) [OR 1.19 (1.05–1.36)], cardiac complications [aOR 1.21 (1.01–1.44)], and stroke [OR 1.39(1.10–1.75)] compared with patients without PAD. Length of stay (LOS) was significantly longer for patients with PAD [7.23 (0.14) days vs. 7.11 (0.1) days, p < 0.001]. Conclusion Of patients undergoing EV‐TAVR, ~25% have coexisting PAD. PAD was not associated with increased risk of in‐hospital mortality but was associated with higher risk of vascular complications, major bleeding, AKI, stroke, cardiac complications, and longer LOS.

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Section: Introductionmentioning

confidence: 99%

“…Furthermore, vascular complications are significantly associated with periprocedural morbidity and mortality. 5,6 However, real-world estimates of PAD prevalence and the association of PAD with in-hospital outcomes in patients undergoing TAVR are limited.…”

Section: Introductionmentioning

confidence: 99%

Association of peripheral artery disease with in‐hospital outcomes after endovascular transcatheter aortic valve replacement

Mohananey

Villablanca

Gupta

et al. 2019

Cathet Cardio Intervent

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“…TAVR: Transcatheter aortic valve replacement; CFA: Common femoral artery; MDCTA: Multidetector computed tomography angiography. Republished with permission of Sage from Sardar et al[ 39 ].…”

Section: Access Techniquesmentioning

confidence: 99%

Vascular complications of transcatheter aortic valve replacement: A concise literature review

Chaudhry¹,

Sardar²

2017

WJC

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Transcatheter aortic valve replacement (TAVR) is a relatively newer therapeutic modality which offers a promising alternative to surgical aortic valve replacement for patients with prohibitive, high and intermediate surgical risk. The increasing trend to pursue TAVR in these patients has also led to growing awareness of the associated potential vascular complications. The significant impact of these complications on eventual clinical outcome and mortality makes prompt recognition and timely management a critical factor in TAVR patients. We hereby present a concise review with emphasis on diverse vascular complications associated with TAVR and their effective management to improve overall clinical outcomes.

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“…As of 1 December 2017, there are 6 CME credits available. 1–6 New CME articles are added to the website every other month, when a new issue of Vascular Medicine is published (six issues per year).…”

Section: Get Cme Credit For Reading Articles In Vascular Medicinementioning

confidence: 99%

CME Opportunities and Save the Date

2017

Vasc Med

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Vascular complications associated with transcatheter aortic valve replacement

Cited by 33 publications

References 92 publications

Association of peripheral artery disease with in‐hospital outcomes after endovascular transcatheter aortic valve replacement

Association of peripheral artery disease with in‐hospital outcomes after endovascular transcatheter aortic valve replacement

Vascular complications of transcatheter aortic valve replacement: A concise literature review

CME Opportunities and Save the Date

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