Introduction
The objective of this study was to evaluate whether a surgery with the use of valved conduit is capable of leading to better immediate and late results than those obtained by the valve-sparing aortic root reconstruction technique.
Methods
Between January 2002 and June 2016, 448 patients underwent aortic root reconstruction. These were divided into three groups according to the technique used: 319 (71.2%) patients received mechanical valved conduits, 49 (10.9%) received biological valved conduits, and 80 (17.9%) underwent the valve-sparing aortic root reconstruction technique. The results were examined by univariate and multivariate analyses of Cox proportional hazards models with multiple logistic regression.
Results
The hospital mortality rate was 7.5%. The mortality rates were 8.2%, 12%, and 2.5% in the mechanical valved conduit, biological valved conduit, and aortic valve-sparing groups, respectively, with no significant difference between groups (
P
=0.1). Thromboembolic complications and reoperation-free survival were also similar (
P
=0.169 and
P
=0.688). However, valve-sparing aortic root replacement was superior in terms of long-term survival (
P
<0.001), hemorrhagic-free survival (
P
<0.001), and endocarditis-free survival (
P
=0.048). Multivariate analysis showed that the following aspects had an impact on mortality: age > 70 years (
P
<0.001; hazard ratio [HR] 1.05), preoperative acute kidney injury (
P
<0.0042; HR 2.9), diagnosis of dissection (
P
<0.01; HR 2.0), previous cardiac surgery (
P
<0.027; HR 2.3), associated coronary artery bypass grafting (
P
<0.038; HR 1.8), reoperation for postoperative tamponade (
P
<0.004; HR 2.2) and postoperative acute kidney injury (
P
<0.02; HR 3.35).
Conclusion
Valve-sparing technique seems to be the operation of choice, whenever possible, for aortic root reconstruction.