Correction: Functional double dissociation within the entorhinal cortex for visual scene-dependent choice behavior

Interactions between stimulus and response types are more strongly represented in the entorhinal cortex than in its upstream regions in rats

“…A Bonferroni-Dunn post hoc test (corrected α = 0.017) revealed significant differences in performance between ACSF and PER-MUS groups (p<0.01) and between ACSF and POR-MUS groups (p<0.001), but not between PER-MUS and POR-MUS groups (p>0.1) ( Figure 2B ). These results suggest that, unlike in the LEC and MEC ( Yoo and Lee, 2017 ), both the PER and POR may play some role in nonspatial behavioral choices made using visual background scenes.…”

“…Rats (n = 7) were trained in the SCN-NSR task as described previously ( Yoo and Lee, 2017 ) ( Figure 2A ). Injection of muscimol (MUS) into either the PER or POR (0.5 μL per site) resulted in significant performance deficits compared with injection of the same volume of artificial cerebrospinal fluid (ACSF) ( Figure 2B ; Figure 2—source data 1 ).…”

“…We tested this by pharmacologically manipulating the PER and POR, the direct upstream regions of the LEC and MEC, respectively, and testing rats in the same scene-based testing paradigms applied in the Yoo and Lee study. Furthermore, as a comparison to the null results reported in the LEC and MEC in object-based behavioral tasks in our previous study, we investigated whether the PER and POR play a role in such tasks ( Yoo and Lee, 2017 ).…”

“…Recently, we reported that the LEC and MEC can be functionally dissociated in scene-memory tasks ( Yoo and Lee, 2017 ). Interestingly, we found that sensory cues interact with task-specific response types.…”

“… Previously we reported results which suggested that response types are critical in dissociating the lateral entorhinal cortex (LEC) from the medial entorhinal cortex (MEC) in a scene memory task ( Yoo and Lee, 2017 ). Here, we investigated whether the perirhinal cortex (PER) and postrhinal cortex (POR), the upstream regions of the LEC and MEC, respectively, could be dissociated similarly.…”