Chronic stress and early recurrence of takotsubo cardiomyopathy: A clinical case

Novo, Giuseppina; Carità, Patrizia; Ajello, Laura; Assennato, Pasquale

doi:10.4103/2211-4122.143976

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…Treatment of TCM is supportive in nature and most patients make a full recovery within a few days or weeks. Recurrence is rare with an annual recurrence rate of approximately 1.5% 10 .…”

Section: Discussionmentioning

confidence: 99%

Mid-Cavity Variant Takotsubo Cardiomyopathy—Magnetic Resonance Imaging Findings

Haran

McBean

Incani³

et al. 2020

Current Problems in Diagnostic Radiology

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“…Treatment of TCM is supportive in nature and most patients make a full recovery within a few days or weeks. Recurrence is rare with an annual recurrence rate of approximately 1.5% 10 .…”

Section: Discussionmentioning

confidence: 99%

Mid-Cavity Variant Takotsubo Cardiomyopathy—Magnetic Resonance Imaging Findings

Haran

McBean

Incani³

et al. 2020

Current Problems in Diagnostic Radiology

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A case report of recurrent takotsubo cardiomyopathy including the rare ‘inverted’ form

Carey

Nucifora

Macnab

2022

European Heart Journal - Case Reports

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Background Takotsubo cardiomyopathy (TC) is a disease that causes transient left ventricular (LV) dysfunction in multiple vascular territories in the absence of coronary artery disease. Takotsubo cardiomyopathy is typically associated with dilation and dyskinesia of the apical and mid-LV segments induced by acute emotional and/or physical stress. Here, we present a case of recurrent TC including one episode of inverted TC, which is a rare form where dyskinesia occurs in the basal segments with sparing of the apical segments. Case summary A 53-year-old female patient with a background history of chronic stress and anxiety was admitted with three episodes of recurrent TC over 4 years. The first episode in 2017 was triggered by an acute stressful event, but no major triggers were identified for the subsequent episodes. Although the first and third episodes displayed the signs of classical TC, the second episode was an inverted TC. Full cardiac function was restored after each episode. She now takes prognostic heart failure medications long term and mental health teams are trying to support her emotional wellbeing. Discussion This patient displayed a rare disease course involving three recurrent episodes of TC, including one instance of its inverted form. Although psychiatric conditions and emotional stress are acknowledged as risk factors for TC, further research is needed to assess whether mental health treatment following TC can prevent disease recurrence.

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Forme Fruste in Recurring Mid-Ventricular Variant of Takotsubo Cardiomyopathy

et al. 2019

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Patient: Female, 69 Final Diagnosis: Mid ventricular type of Takotsubo cardiomyopathy Symptoms: Chest discomfort Medication: — Clinical Procedure: Angiography • 2D echocardiogram Specialty: Cardiology Objective: Unusual clinical course Background: Takotsubo cardiomyopathy (TC) is characterized as acute left ventricular dysfunction precipitated by intense emotional or physiological stress. The mid-ventricular variant of TC usually has akinesis, with or without ballooning of the mid-ventricular segment, and a hyperdynamic base and apex. Recurrence of the typical and atypical (reversed and mid-ventricular type) forms has been reported in only a very small number of cases. We report a forme fruste presentation of mid-ventricular variant of TC. Case Report: A 69-year-old woman with a prior history of stress-induced cardiomyopathy presented with complaint of moderate intensity, persistent, sub-sternal chest discomfort. She reported that her symptoms were similar to those she had during a previous hospitalization in 2015, and this time cited the death of her mother as an inciting stressor. No significant obstructive flow-limiting coronary artery disease was found on cardiac catheterization. However, the left ventriculogram was suggestive of mid-ventricular pattern of TC. Her first symptomatic episode of apparent TC did not reveal completion of the mid-ventricular pattern of the TC variant. The subsequent episode, during this hospitalization, manifested as a completed version of her initial apparent forme fruste of mid-ventricular variant of TC. Conclusions: TC may present in a myriad of clinical forms that must be considered in the evaluation of patients with suspected acute coronary syndromes or cardiomyopathy. Treatment is mainly supportive, and recurrence rates range from 7.7% to 11.4%. To the best of our knowledge, this forme fruste presentation has not been previously reported in recurrent variants of TC.

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Chronic stress and early recurrence of takotsubo cardiomyopathy: A clinical case

Cited by 5 publications

References 9 publications

Mid-Cavity Variant Takotsubo Cardiomyopathy—Magnetic Resonance Imaging Findings

Mid-Cavity Variant Takotsubo Cardiomyopathy—Magnetic Resonance Imaging Findings

A case report of recurrent takotsubo cardiomyopathy including the rare ‘inverted’ form

Forme Fruste in Recurring Mid-Ventricular Variant of Takotsubo Cardiomyopathy

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