Urinary tract infections in kidney transplant recipients 1^st year after transplantation

Abstract

Background:One of the main causes of adverse complications following kidney transplantation is urinary tract infection (UTI). This study was done to define the incidence rate, clinical profiles, causative microorganisms, and UTI risk factors among kidney transplant recipients in Mashhad city.Materials and Methods:In this retrospective study, we perused medical files of 247 kidney recipients who underwent transplant surgery at Mashhad University Montaserie Hospital, during 2012–2014. All patients were followed for UTI during the 1st year after surgery.Results:75 episodes of UTI developed by 152 pathogens in 56 (22.7%) of patients during 1-year follow-up. 26.6% of total UTIs were diagnosed within the 1st month after transplantation. The most frequently isolated uropathogens were Escherichia coli (55.3%, n = 84). The high rate of candiduria (8.5%) was observed, too.Conclusion:UTI is known as one of the hospitalization reasons in kidney transplantation recipients. Defining appropriate antibiotic prophylaxis against bacterial and fungal agents and early removal of urethral catheter are suggested to decrease posttransplantation complications.

Role of Contrast-Enhanced Voiding Urosonography in the Evaluation of Renal Transplant Reflux – Comparison with Voiding Cystourethrography and a New Classification

“…UTI is the most frequent infectious complication reported in the literature, among patients with renal transplant, and it is con- sidered the most important risk factor for weak graft function, morbidity, and mortality [16]. The pathogens most frequently encountered in this study were Klebsiella, Escherichia coli, and BKV.…”

<p>Characterization of Extended-Spectrum β-Lactamase-Producing Uropathogenic <em>Escherichia coli</em> Among Iranian Kidney Transplant Patients</p>

“…It is considered a particular risk factor for graft loss and patient death in kidney recipients, and it has seen in the first few weeks following transplantation. 20 Gram-negative bacteria are the leading cause of 70% of UTIs, leading to renal failure of which, UPEC is the most common etiology. Furthermore, the extensive use of antibiotics in human medicine as treatment, prevention, and prophylactic is associated with the increasing emergence of MDR and ESBL-producing strains.…”

Molecular characterization of ESBL-producing uropathogenic Escherichia coli isolates among kidney transplant patients: Emergence and spread of B2-ST131 clone type

“…Transplantation of the kidney is the best treatment for patients with end-stage renal disease. This medical procedure not only enhances the quality of life but also extends the life expectancy of the patients [ 1 , 2 ]. However, transplantation is not without complications, and various life-threatening infections may develop in these patients [ 3 ].…”