Population data of 23 autosomal STR loci in the Chinese Han population from Guangdong Province in southern China

Yang, Lijing; Zhang, Xiufeng; Zhao, Lijuan; Sun, Yanan; Li, Jiajue; Huang, Renwu; Hu, Liping; Nie, Shengjie

doi:10.1007/s00414-017-1588-4

Cited by 21 publications

(11 citation statements)

References 9 publications

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“…Pairwise genetic distance (F ST ) and p-values were calculated for each locus between populations using Arlequin V3.5 software 11 . Further, a phylogenetic tree and a principal component analysis (PCA) plot showing the interpopulation relationship were constructed using Poptree 2 12 and Past 3.11 13 software, respectively, according to the allelic frequency data of Liannan Yao population and 8 other reported populations (Guangxi Yao 14 , Jiangxi Han 15 , Sichuan Han 16 , Fujian Han 17 , Hunan Han 18 , Fujian She 19 , Guangdong Han 20 , and Hebei Han 21 populations).…”

Section: Methodsmentioning

confidence: 99%

Genomic Portrait of Guangdong Liannan Yao Population Based on 15 Autosomal STRs and 19 Y-STRs

Liao

Chen

Huang

et al. 2019

Sci Rep

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Here we studied the genetic polymorphism and evolutionary differentiation of the Guangdong Liannan Yao population based on 15 autosomal STR loci and 19 Y chromosomal STR loci. The blood card DNA of 302 unrelated individuals from the Yao Autonomous County of Liannan was directly amplified using an Expressmarker 16 + 19Y kit and genotyped using a 3500XL Genetic Analyzer. For the autosomal STR loci, the CPD value was over 0.999 999 999 999, while the CPE value was over 0.9999. The population comparison revealed a closer relationship between the Liannan Yao population and the She ethnic population than other reported Chinese populations. For the Y-STRs, a total of 102 unique haplotypes were obtained, 87 of which were observed only once. Both RST pairwise analysis and a multidimensional scaling plot showed that the Liannan Yao population is closely related to the Fujian She ethnic population and is significantly different from other Chinese ethnic populations. The results show that the 15 autosomal STR and 19 Y-STR loci are valuable for forensic applications and human genetic studies in the Liannan Yao population.

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Section: Methodsmentioning

confidence: 99%

Genomic Portrait of Guangdong Liannan Yao Population Based on 15 Autosomal STRs and 19 Y-STRs

Liao

Chen

Huang

et al. 2019

Sci Rep

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“…To explore the genetic background of the studied Kazak group in Nilka county, the genetic relationships between the Kazak group and 20 reference populations (only allelic frequencies were available without raw data) were performed based on allelic frequencies of the same 15 autosomal STR loci mentioned above. These reference populations included Northern Han [ 29 ], Shanghai Han [ 30 ], Guangdong Han [ 31 ], Henan Han [ 32 ], Hui [ 33 ], Tibetan [ 34 ], Ewenki [ 35 ], Kazak in Xinjiang [ 36 ], Kazak in Barkol [ 37 ], Zhuang [ 38 ], Dai [ 38 ], Li [ 39 ], Yi [ 40 ], Dong [ 41 ], She [ 42 ], Bouyei [ 43 ], Tujia [ 44 ], Gelao [ 44 ], Italian [ 45 ] and Estonian [ 46 ] populations.…”

Section: Resultsmentioning

confidence: 99%

Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations

Wang

Jin

Zhang

et al. 2020

Forensic Sciences Research

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Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method. In this study, allelic frequencies and forensic statistical parameters of the 19 autosomal STR loci in a Kazak ethnic group were calculated, and its genetic relationships with reference populations were assessed in order to understand population structure better and enrich population genetic data for forensic practice in Chinese Kazak ethnic group. There were 226 identified alleles with the corresponding allelic frequencies ranging from 0.0008 to 0.5295 in the 628 unrelated healthy Kazak individuals in Xinjiang Uygur Autonomous Region. All autosomal STRs were conformed to the Hardy-Weinberg equilibrium after Bonferroni’s correction. The cumulative power of discrimination and the combined probability of exclusion of all the 19 autosomal STRs were 0.999 999 999 999 999 999 999 997 162 and 0.999 999 994 484, respectively. Furthermore, the D A distances and Fixation index values of pairwise populations, principal component analysis, multidimensional scaling analysis, phylogenetic tree analysis and structure analysis were conducted to probe the genetic relationships between the Kazak group and other reference populations. The population genetic results showed that these 19 autosomal STR loci were characterised by high genetic diversities in the Kazak group. Furthermore, the studied Kazak group had close genetic relationships with the Uyghur group and the Uzbek group. The present results may facilitate understanding the genetic background of the Chinese Xinjiang Kazak group.

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“…For the purpose of ascertaining the genetic similarity and diversity between our three studied populations and 14 previously reported Chinese populations (Han 9,15,16,18–21 , Yi 16 , Tibetan 9,16 , Uygur 9,17,23 and Kazakh 22 populations), Nei’s standard genetic distances were calculated (Supplementary Table S14 and Fig. S2).…”

Section: Resultsmentioning

confidence: 99%

Genetic polymorphism and phylogenetic differentiation of the Huaxia Platinum System in three Chinese minority ethnicities

Liu

Wang

et al. 2019

Sci Rep

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Short tandem repeats (STRs) with features of high polymorphism and abundant evolution information play a significant role in genetic applications such as human forensics, anthropology and population genetics. The Huaxia Platinum System was specifically exploited to allow coamplification of all markers in the expanded Combined DNA Index System and the Chinese National Database. Herein, in continuation of our previous studies, 493 unrelated individuals were firstly genotyped to investigate the efficacy of this novel system in three minority ethnicities of China (Hui, Tibetan and Uygur). Additionally, genetic relationships among our three investigated populations and other previously published populations were analyzed using pairwise genetic distances, multidimensional scaling (MDS), principal component analysis (PCA), cladogram and STRUCTURE. The combined match probabilities (CMP) for the Hui, Tibetan and Uygur groups were 1.6894 × 10 −27 , 6.1666 × 10 −27 and 5.0655 × 10 −27 , respectively, and the combined powers of exclusion (CPE) were 0.999999999646627, 0.999999999304935 and 0.999999999433994. Population comparison analysis manifested that the Hui and Tibetan populations had genetic affinities with the Han, Yi and Korean populations, while the Uygur group had a close relationship with the Kazakh population. The aforementioned results suggested that the Huaxia Platinum System is a polymorphic and effective tool that is appropriate for personal identification and population genetics.

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Population data of 23 autosomal STR loci in the Chinese Han population from Guangdong Province in southern China

Cited by 21 publications

References 9 publications

Genomic Portrait of Guangdong Liannan Yao Population Based on 15 Autosomal STRs and 19 Y-STRs

Genomic Portrait of Guangdong Liannan Yao Population Based on 15 Autosomal STRs and 19 Y-STRs

Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations

Genetic polymorphism and phylogenetic differentiation of the Huaxia Platinum System in three Chinese minority ethnicities

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