Muscle strength rather than muscle mass is associated with osteoporosis in older Chinese adults

Ma, Yixuan; Fu, Liyuan; Jia, Liye; Han, Peipei; Li, Kang; Yu, Hairui; Chen, Xiaoyu; Yu, Xinguang; Hou, Lin; Wang, Lu; Zhang, Wen; Niu, Kaijun; Guo, Qi

doi:10.1016/j.jfma.2017.03.004

Cited by 37 publications

(30 citation statements)

References 39 publications

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“…However, the majority of participants in that study were women. Conversely to the previously mentioned ndings, one cross-sectional study in China found no differences between skeletal muscle mass index in older adults and T-score [27]. It should be noted that in this study,BMD was not measured by the DXA, but by the quantitative ultrasound at calcaneus.…”

Section: Discussioncontrasting

confidence: 93%

“…Femoral neck and hip BMD and T-score as well as whole body T-score and BMC were correlated with handgrip strength. In older Chinese adults, higher handgrip strength was associated with lower risk of osteoporosis [27]. Although, in older Chinese women with osteoporosis, handgrip strength was correlated with femoral neck, hip and lumbar spine BMD, in the same study such correlations were not found in men's group [30].…”

Section: Discussionmentioning

confidence: 76%

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Associations Between Muscle Mass, Muscle Morphology and Bone Health in Older Men With Sarcopenia: A Cross-sectional Study

Mastavičiūtė

Kilaite²,

Petroška³

et al. 2020

Preprint

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Background: The aim of this study was to explore the association between muscle mass, morphology, bone mineral density, and physical function in community-dwelling older men with sarcopenia.Methods: A total of 151 men, 60 years or older were included in this study. Body composition was measured by dual-energy X-ray absorptiometry (DXA). Low bone mineral density was diagnosed if T-score was equal to or below -1.0 SD of mean young men reference range. Sarcopenia was diagnosed according to European Working Group on Sarcopenia in Older People (EWGSOP) criteria: low muscle mass and low muscle strength or low physical performance. Physical performance was evaluated by short physical performance battery. Microbiopsy of musculus vastus lateralis was performed with disposable muscle microbiopsy system. The perimeter and cross-section area of muscle fibers were calculated using image analysis software in whole slide images; type of fiber and their distribution were evaluated as well. Relationship between variables were examined using Spearman’s and Pearson’s correlations. The level of significance (p-value) of < 0.05 was considered as statistically significant.Results: Mean age of the subjects was 72.9 ± 8.02 years. Sarcopenia was diagnosed in 45 (29.8%) men. In the sarcopenia group, 25 muscle biopsies were examined. The average muscle fiber length was 217.47 ± 25.22 microm and average fiber cross-sectional area was 2446 ± 608.87 microm2. In 9 sarcopenic men with T-scores equal or below -2.5, the muscle fiber area had a significant correlation with balance test (r = 0.73, p = 0.025). Multiple significant correlations were found between bone mineral density, lean mass, appendicular lean mass, arm and leg lean mass, gait speed, balance test and handgrip strength.Conclusions: In men with sarcopenia, low lean muscle mass was associated with low femoral neck and hip BMD, and lower muscle strength. In sarcopenic men with osteoporosis, lower muscle fiber area was associated with lower scores of balance test.Trial registration: study protocol has been approved by Lithuanian regional biomedical research ethics committee (No. 158200-03-208-75).

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Section: Discussioncontrasting

confidence: 93%

Section: Discussionmentioning

confidence: 76%

Associations Between Muscle Mass, Muscle Morphology and Bone Health in Older Men With Sarcopenia: A Cross-sectional Study

Mastavičiūtė

Kilaite²,

Petroška³

et al. 2020

Preprint

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“…A striking finding in our study was a significant positive correction between MMI and BMD of the femur and the spine, these results are consistent with a meta-analysis published in 2014 that includes 15,260 women between 18 and 92 years where muscle mass has a positive relation with BMD of the femoral neck, with the data adjusted for age (26). However, there are studies that refute this hypothesis, like a population in China that includes 516 men and 652 older women and no relation between the muscle mass and risk of osteoporosis was found (p = 0.205) (27). There are no local studies that can compare our results.…”

Section: Discussionsupporting

confidence: 90%

Correlation of Muscle Strength and Mass with Bone Mineral Density in Postmenopausal Women

Martínez

Saavedra

Rojas³

et al. 2019

IMMINV

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Introduction: Osteoporosis is a systemic disease of the bone, which entails an increased riskof fracture, with high impact on morbidity, mortality and costs in the health system. Severalstudies have shown a relationship between muscle mass and strength with bone mineral density.Our objective is to determine the correlation between these variables in postmenopausalwomen. Materials and Methods: For the correlation study, 100 postmenopausal womenolder than 50 years were selected randomly and a sociodemographic survey was conducted,and muscle strength was determined by manual grip strength, which was measured with adigital dynamometer. Bone mineral density measurements and muscle mass were obtainedwith densitometry. The correlation between strength, muscle mass, and bone mineral densitywas determined by a Spearman correlation. Results: The average age was 62.8 ± 7.48. Femurand column bone mineral density were significantly related to the muscle mass index, weight,and body mass index. The prevalence of fragility fracture was 17%. The bone mineral densityof the femur was lower in patients with fragile fracture, and there was a negative and significantcorrelation between femur bone mineral density and skeletal muscle mass index. Conclusion:Bone health studies should include the study of muscle mass index and the skeletal musclemass index. The improvement of the muscle mass index can influence femoral and vertebralbone mineral density with significant impact on fragility fractures. This is the first study of itskind conducted in Colombia and South America.

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“…Such adaptations in physically inactive and sedentary participants may aid in their ability to perform a range of movements with precision and confidence in a variety of scenarios [1]. This can facilitate the improvement of health and fitness, enhance physical performance, reduce the relative risk of injury, and develop confidence and competence [1] in trainees, potentially leading toward reduced mortality [2], cardiovascular disease [3], among other health-markers improvements [4].…”

Section: Discussionmentioning

confidence: 99%

“…Habitual development of these qualities may improve health and fitness, enhance physical performance, reduce the relative risk of injury, and develop confidence and competence [1]. Moreover, poor muscular fitness is associated with mortality [2], cardiovascular disease [3], among other health markers [4], with recent findings demonstrating an alarming trend towards reduced muscular fitness in young population over the years [5], a reduction that showed accelerated rates in recent decades [6].…”

Section: Introductionmentioning

confidence: 99%

Effects of Traditional Strength Training Versus Jump Training on Muscular Fitness among Physically Inactive and Sedentary Young Adults

Torres-Banduc

Ramírez‐Campillo

García‐Pinillos

et al. 2020

TOSSJ

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Background: The effects of Traditional Resistance Training (TRT) and Plyometric Jump Training (PJT) had never been compared in participants that are both sedentary and physically inactive. Results derived from such research may allow important practical applications. Objective: The aim of this study was to compare the effects of 4-weeks of TRT versus PJT programs on the muscular fitness of sedentary and physically inactive participants. Methods: Baseline and follow-up tests included the assessment of Squat Jump (SJ), Countermovement Jump (CMJ), elastic index, and maximal strength of the knee extensors (MVS). Males and females (age range, 18-29 years) were randomly assorted into a control group (CG, n=11), TRT (n=8), and PJT groups (n=9). The TRT program emphasized slow-speed movements with free weights. The PJT program emphasized high-speed jump movements without external loads. Both TRT and PJT sessions lasted 30-minutes. Dependent variables were analyzed in separate three (Groups) × two (Time: pre, post) ANOVA, with Bonferroni-adjusted α (p<0.05). Results: Main effects of time (all p<0.05) were observed for SJ (ηp2 = 0.51), CMJ (ηp2 = 0.33), and MVS (ηp2 = 0.33). Post-hoc analyses revealed similar significant (all p<0.05) improvements in the TRT and PJT groups for SJ (∆, 95%CL, 9.0-22.5%), CMJ (∆, 95%CL, 11.7-24.4%), and MVS (∆, 95%CL, 5.8-21.3%). No significant changes were observed in the control group. No changes were observed for the elastic index. Conclusion: In otherwise healthy participants that are both physically inactive and sedentary, both TRT and PJT protocols are equally effective in improving the muscular fitness.

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Muscle strength rather than muscle mass is associated with osteoporosis in older Chinese adults

Abstract: Based on our study, muscle strength rather than muscle mass is negatively associated with OS in older people; thus, we should pay more attention to muscle strength training in the early stage of the OS.

Cited by 37 publications

References 39 publications

Associations Between Muscle Mass, Muscle Morphology and Bone Health in Older Men With Sarcopenia: A Cross-sectional Study

Associations Between Muscle Mass, Muscle Morphology and Bone Health in Older Men With Sarcopenia: A Cross-sectional Study

Correlation of Muscle Strength and Mass with Bone Mineral Density in Postmenopausal Women

Effects of Traditional Strength Training Versus Jump Training on Muscular Fitness among Physically Inactive and Sedentary Young Adults

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