A reduced 12-joint ultrasound examination predicts lack of X-ray progression better than clinical remission criteria in patients with rheumatoid arthritis

Miguel, Eugenio de; Pecondón-Español, Ángela; Castaño-Sánchez, Manuel; Corrales, Alfonso; Gutierrez-Polo, Ricardo; Rodríguez–Gómez, Manuel; Pinto-Tasende, J.; Rivas, Jose Luis; Ivorra-Cortés, José

doi:10.1007/s00296-017-3714-5

Cited by 11 publications

(6 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On one hand, the lack of ultrasound activity predicts achievement and persistence of remission (33,34). On the other hand, there is a very high degree of confidence that residual synovial activity is a significant predictor for loss of remission (relapse, flare) and radiographic progression since controlled studies (35)(36)(37), meta-analyses (38,39), magnetic resonance imaging (MRI) studies (40)(41)(42)(43)(44)(45)(46), biological markers (14) and histology (47,48) have confirmed the cited ultrasound observations. The loss of remission tends to happen in the first year of follow-up (39), especially if treatment is withdrawn (49,50).…”

Section: Introductionmentioning

confidence: 71%

Clinical and ultrasound ankle involvement in rheumatoid arthritis in remission

Enache¹,

Popescu²,

Codreanu³

et al. 2019

Ro J Rheumatol.

View full text Add to dashboard Cite

Objective. We aimed to evaluate the prevalence and differences of clinical and ultrasound involvement of ankles in rheumatoid arthritis (RA) patients in remission. Methods. RA patients were recruited in 2018 in the random order of presentation from the outpatient clinic. In the day of enrolment, all patients underwent clinical examination (by a senior rheumatologist, blind to other evaluations), inflammatory markers (e.g. C-reactive protein-CRP) and ankle ultrasound (performed and interpreted by a single rheumatologist with more than 7 years of experience). Results. The sample included 59 patients in DAS28CRP remission, 27 in SDAI remission and 20 in Boolean remission. Among these 3 categories of remission, overall clinical ankle involvement presented similar prevalence (revolving around 30%). On average, 77% of patients presented overall ultrasound ankle involvement among the 3 categories of remission, with similar frequencies of ankle joint synovial hypertrophy (SH; 33%), power Doppler (PD) positive joint SH (15%), ankle joint effusion (60%), ankle tenosynovitis (27%) and PD positive ankle tenosynovitis (15%). In the subgroup of RA patients in DAS28CRP remission, compared to patients without clinical or ultrasound ankle involvement, those with at least one involved ankle had a significantly higher median CRP (0.34 mg/dl versus 0.19 mg/dl, p = 0.042). Conclusion. Among RA patients in remission, regardless of its definition, clinical and ultrasound involvement of ankles is frequent. Clinical and ultrasound screening of ankles in RA patients in remission seems an appropriate strategy.

show abstract

Section: Introductionmentioning

confidence: 71%

Clinical and ultrasound ankle involvement in rheumatoid arthritis in remission

Enache¹,

Popescu²,

Codreanu³

et al. 2019

Ro J Rheumatol.

View full text Add to dashboard Cite

show abstract

“…Such information should not be underestimated from a clinical point of view. Considering that the goal of the treatment is to arrest disease progression, it might be advisable to add the lack of signal in PDUS examination to remission criteria [40].…”

Section: Results -Selective Application Of Ultrasonography Testingmentioning

confidence: 99%

“…On the other hand, the lack of a PD signal is strongly correlated with the lack of radiological change progression in RA patients [ 36 , 40 ]. Such information should not be underestimated from a clinical point of view.…”

Section: Discussionmentioning

confidence: 99%

The changing role of ultrasonography examination in patients with rheumatoid arthritis in light of recent studies

Dura¹,

Żuchowski²,

Gorgolewski³

et al. 2020

Reumatologia

View full text Add to dashboard Cite

For many years, ultrasonography (US) has been a widely accepted modality used for joint assessment in patients with rheumatoid arthritis (RA). Given the efficacy of present day therapies, there is scepticism whether it is required in the first place. The most recent clinical Targeting synovitis in Early Rheumatoid Arthritis (TaSER) and Clinical Tight Control Therapy (ARCTIC) trials' results appear to contradict it, yet this does not necessarily mean ultrasound has no place in modern rheumatology. The possibility of detecting inflammation at a subclinical level carries a tremendous predictive value, enabling identification of patients likely to experience an exacerbation in the coming months. Therefore, US should be a part of the decision-making process regarding treatment modification or introduction of any additional interventions, such as glucocorticosteroid injections. The results of the most recent clinical trials do not negate the usefulness of US, but merely suggest that it ought to be used in moderation.

show abstract

“…These movements 7 need the knee joint to be satisfactorily perfect . The incidence of knee pain in japan is very high which is 27.3%, 8,9 While it is relatively low in America 12-13% . are well known.…”

Section: Introductionmentioning

confidence: 97%

Multiparity as a Potential Cause of the Articular Cartilage Degradation in the Knee Joint; Sonographic Evaluation in the Postmenopausal Women

Javed¹,

Bacha²,

Khadija³

et al. 2022

Annals KEMU

View full text Add to dashboard Cite

Background: Pain in knee joint is prime cause of disability particularly among postmenopausal women. Ultrasound is a non-invasive and safe imaging modality for the evaluation of knee joint pathologies. Objective: To prove multiparity as a potential cause of femoral cartilage thinning inside knee joint causing pain in postmenopausal women. Methodology: Two hundred knee of 100 postmenopausal women of various parity were conveniently selected. Patients with all other risk factors of the knee joint pain which acts as effect modifying factors were excluded. Femoral articular cartilage was measured at the lateral, central and medial aspect of the knee joint and their average was calculated. Results: 51.12 ±4.46 years was the mean age of patients (ranging from 46 to 60 years). A strong negative relation was found between the parity of the patient and the femoral articular cartilage thickness at the lateral, central and medial aspect of the knee joint of all the patients with a p-value less than 0.1. Significant variation was observed in the femoral articular cartilage thickness in various parties. Conclusion: The femoral articular cartilage decreases in size significantly with an increase in the number of deliveries (parity). So, multiparity is one of the potential causes of femoral cartilage degradation in knees joint.

show abstract

A reduced 12-joint ultrasound examination predicts lack of X-ray progression better than clinical remission criteria in patients with rheumatoid arthritis

Cited by 11 publications

References 34 publications

Clinical and ultrasound ankle involvement in rheumatoid arthritis in remission

Clinical and ultrasound ankle involvement in rheumatoid arthritis in remission

The changing role of ultrasonography examination in patients with rheumatoid arthritis in light of recent studies

Multiparity as a Potential Cause of the Articular Cartilage Degradation in the Knee Joint; Sonographic Evaluation in the Postmenopausal Women

Contact Info

Product

Resources

About