MULTIHORMONAL ISLET CELL CARCINOMAS IN THREE KOMODO DRAGONS (<i>VARANUS KOMODOENSIS</i>)

Eustace, Ronan; Garner, Michael M.; Cook, Kimberly; Miller, Christine; Kiupel, Matti

doi:10.1638/2016-0131.1

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…Limited description of the mesenteric tear did not indicate chronicity of the rent, but there was no report of the patient having undergone surgery previously (Wills et al ., 2016). A case series from 2017 also referred to a case of mesenteric torsion with 360° rotation in a Komodo dragon ( Varanus komodoensis ) (Eustace et al ., 2017). This was found on postmortem examination after the patient had been found dead.…”

Section: Discussionmentioning

confidence: 99%

Intestinal Torsion and Volvulus Through a Mesenteric Rupture in a Bearded Dragon (Pogona vitticeps)

Hornby,

Hedley,

Spiro

2023

Journal of Herpetological Medicine and Surgery

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A female spayed bearded dragon (Pogona vitticeps) of unknown age presented with a 48-hour history of anorexia and lethargy. On presentation, the patient had a black beard, sunken eyes and a full coelomic cavity on palpation, although no specific thickening or masses were noted. Diagnostic investigations were conducted in the form of radiographs and ultrasonography. The owner elected euthanasia due to deterioration in the patient’s condition. Gross and microscopic post-mortem examination revealed a torsion and volvulus of the gastrointestinal tract through a rupture in the mesentery, with marked red/black, segmental discolouration to the intestines. Limitations of this study include no further diagnostic tests other than imaging and decision to euthanise hindering the ability to explore surgical correction. To the authors’ knowledge, this is the first reported case of intestinal torsion and volvulus through a mesenteric rupture in a bearded dragon.

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Section: Discussionmentioning

confidence: 99%

Intestinal Torsion and Volvulus Through a Mesenteric Rupture in a Bearded Dragon (Pogona vitticeps)

Hornby,

Hedley,

Spiro

2023

Journal of Herpetological Medicine and Surgery

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“…Similar to other taxa, various etiologies have been proposed, such as environmental, genetic, and infectious causes [3][4][5][6][7]. Several reports hypothesize species predispositions for certain neoplasms such as gastric neuroendocrine carcinoma in bearded dragons and pancreatic masses in Komodo dragons [4,8]. As advanced care is increasingly utilized in lizards, treatment is also more commonly being pursued for neoplasia.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Neoplasia, Treatments, and Survival in Lizard Species

Willig,

Torpy,

Harrison

et al. 2024

Animals

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Neoplasia has been reported in lizards, but more research is needed to accurately document the prevalence and prognosis of the various known neoplasms that affect lizards. This study reviewed medical records from an online database, the Exotic Species Cancer Research Alliance (ESCRA), and reviewed published literature to determine the prevalence of neoplasia, malignancy, metastasis, treatment strategies, and outcomes by species and sex. Records from 55 individual lizards, 20 different species, and 37 different tumors were identified. In the literature, 219 lizards, 59 species, and 86 unique tumors were identified from 72 published case reports. Potential signalment factors such as age, sex, and species were evaluated to see if they affected case outcome. Additional factors including neoplasia type, presence of metastasis, and types of pursued treatments were also evaluated. Statistical analysis was performed to determine whether a factor was significantly associated with animal death due to the identified neoplasia or with animal survival or death due to other causes (non-neoplastic outcomes). Komodo dragons and savannah monitors were more likely to die from neoplasia compared to other lizard species. Cases where the status of metastasis was unknown were significantly associated with death due to neoplasia. Having an unknown status of male versus female was significantly associated with non-neoplastic outcomes of death. Leukemia and islet cell carcinoma were significantly associated with death due to neoplastic causes. Chondrosarcoma, myxosarcoma, osteosarcoma, and squamous cell carcinoma were significantly associated with non-neoplastic outcomes of death. Surgery alone and radiation therapy alone each were significantly associated with non-neoplastic outcomes of death, while lizards not receiving treatment were significantly associated with death due to neoplasia. Benign neoplasia was significantly associated with non-neoplastic outcomes of death. These results will aid in the improved diagnosis and management of neoplasia in lizard species, as well as expanding our understanding of prognostic indicators of neoplasia in lizards.

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Gastroenterology—Small Intestine, Exocrine Pancreas, and Large Intestine

Eatwell¹,

Richardson²

2019

Mader's Reptile and Amphibian Medicine and Surgery

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MULTIHORMONAL ISLET CELL CARCINOMAS IN THREE KOMODO DRAGONS (VARANUS KOMODOENSIS)

Cited by 4 publications

References 10 publications

Intestinal Torsion and Volvulus Through a Mesenteric Rupture in a Bearded Dragon (Pogona vitticeps)

Intestinal Torsion and Volvulus Through a Mesenteric Rupture in a Bearded Dragon (Pogona vitticeps)

Evaluation of Neoplasia, Treatments, and Survival in Lizard Species

Gastroenterology—Small Intestine, Exocrine Pancreas, and Large Intestine

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