Suspected Synthetic Cannabinomimetic Intoxication: Case Series and Review

Abstract

Recent legislation has failed to curb the public health concerns emanating from SC misuse. Education about the risks of SC use along with additional regulation may be required to remove the false sense of safety that some individuals, especially adolescents and young adults, may associate with these compounds, which are often misconstrued as "herbal marijuana." Clinicians need to be prepared to identify and treat symptoms of SC intoxication as incidents of toxicity continue to rise.

Drugs of abuse and ocular effects

“…168 Male teenagers and young adults are some of the most targeted customers for this type of drugs. 169 This group of substances is a growing public health concern, since they are easy to purchase on the internet, inexpensive and not yet detectable on the screening tests. 170,171 One new psychoactive substance is synthetic cannabinoid, which imitates the effect of cannabis, with D9tetrahydrocannabinol.…”

“…170,171 One new psychoactive substance is synthetic cannabinoid, which imitates the effect of cannabis, with D9tetrahydrocannabinol. 169 There are many names of this drug, including K2, Spice, Aroma, Dream, Bonzai, herbal smoking mixtures, air fresheners, herbal blends, Black Mamba, Pandora's Box, Clockwork Orange, Cherry Bomb, Sweet Leaf, Pandora Reborn. [172][173][174] The literature reports more than 160 different synthetic cannabinoid available on the market.…”

Medical Cannabis and School: Separating Fact From Fiction

“…While THC from plant sources is a partial agonist at CB1 receptors, many synthetic compounds are full agonists and are dramatically more potent, leading to more intense psychoactive and physical effects including toxicity and death. Symptoms most often observed included agitation, altered level of consciousness, and dilated pupils (Baum, Bailey, Chan, & Blumenschein, 2017).…”