Laparoscopic Versus Open Resection for Gastric Gastrointestinal Stromal Tumors (GISTs): A Size–Location‐Matched Case–Control Study

Chi, Jun-Lin; Xu, Mao Jin; Zhang, Ming-Ran; Li, Yuan; Zhou, Zong‐Guang

doi:10.1007/s00268-017-4005-8

Cited by 23 publications

(16 citation statements)

References 38 publications

(31 reference statements)

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“…In the study by Chi. et.al, oral intake was 3.5 days but the mean hospital stay was 6.1 days [20]. In our series, patients had a smooth postoperative course apart from blood transfusion for two cases due to anemia and another had pneumothorax necessitating chest tube insertion.…”

Section: Discussionmentioning

confidence: 45%

“…In the laparoscopic group, six patients had either local recurrence or distant metastasis and four of these patients died, while, in the open group, ten had either local recurrence or distant metastasis and ve of them died. These results indicate that laparoscopic surgery for gastric GISTs has oncologic outcomes similar to that of open surgery [20].…”

Section: Discussionmentioning

confidence: 57%

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Laparoscopic Partial Gastrectomy for Large Gastric GISTs

Abouzid

Fathi

Shetiwy

2021

J Gastrointest Canc

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Background: Gastrointestinal stromal tumors (GISTs) are considered the most common mesenchymal tumors in the gastrointestinal tract and the stomach is the most frequently site affected (50-60%). The safety and feasibility of laparoscopic surgery for gastric GISTs of sizes larger than 5 cm remains unclear.It depends on the surgical skills, tumor location and the learning curve of the surgeons.Methods: Between December 2013 and January 2021, thirty patients diagnosed with gastric GISTs underwent laparoscopic partial gastrectomy. This is a retrospective study done in surgical oncology unit, Oncology Center, Mansoura University, Egypt.Results: The most common tumor location was in the greater curvature in (46.7%). The mean tumor size was 7.2 cm (the largest was 13 cm). All of the patients underwent laparoscopic partial gastrectomy.Splenectomy was done for one patient only. The mean operative time was 152.67 minutes and the estimated blood loss (EBL) was 139.33 ml. The mean hospital stay was 3.53 days. The mean follows up period was 32.4 months. Conclusion:Laparoscopic resection for gastric GISTs has become a feasible method. Patients with large tumors have the same favorable outcomes as small tumors. Large-sized GISTs may receive neoadjuvant therapy to downstage the disease and make it amenable for laparoscopic resection.

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Section: Discussionmentioning

confidence: 45%

Section: Discussionmentioning

confidence: 57%

Laparoscopic Partial Gastrectomy for Large Gastric GISTs

Abouzid

Fathi

Shetiwy

2021

J Gastrointest Canc

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“…Laparoscopic surgery is less invasive compared with open surgery [ 13 – 16 ]. In addition, umbilical single-incision laparoscopic surgery (SILS) is cosmetically superior to open surgery [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

A rare case of perivascular epithelioid cell tumor (PEComa) of the greater omentum

et al. 2018

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BackgroundA tumor composed exclusively or predominantly of human melanin black 45 (HMB45)-positive epithelioid cells is called a perivascular epithelioid cell tumor (PEComa). We report a very rare case of a PEComa of the greater omentum.Case presentationMRI conducted to examine the orthopedic disease of the patients, a 49-year-old Japanese woman, also identified a tumor in her pelvis. A CT scan revealed a tumor mass on the right side of the pelvic floor and clear nutrient vessels originating from the splenic and celiac arteries. An omental primary tumor or accessory spleen was thus suspected, and tumor resection was performed. The tumor was a light brown solid tumor with a smooth margin, measuring 5.2 × 3.8 × 3.5 cm. Histopathologically, the tumor was composed mainly of spindle and epithelioid cells, and large and small blood vessel formation was observed. In the immunohistochemical staining, tumor cells were positive for human melanin black 45 (HMB-45) and Melan-A and partially positive for alpha-smooth muscle actin. The final diagnosis was PEComa of the greater omentum.ConclusionsAlthough omental PEComa is very rare, it should be considered as a differential disease of an omental primary tumor.

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“…There are many papers on the safety of laparoscopic resection; however, most often they refer only to gastric GIST. The achieved oncological results are comparable to open surgery [19,20,21,22]. Currently, laparoscopic resection is permissible in tumors below 10 cm in maximal diameter and when the risk of local recurrence is low even after R1 resection; however, the size limits of tumors are constantly shifted.…”

Section: Laparoscopy/endoscopy In the Treatment Of Gistmentioning

confidence: 92%

Is the Surgical Margin in Gastrointestinal Stromal Tumors Different

2018

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Background: Radical surgical excision is the mainstay of therapy of primary, nonmetastatic gastrointestinal stromal tumors (GIST) and margin status after surgery is a significant prognostic factor. Methods and Results: The aim of this paper is to review principles in primary GIST surgery, i.e. differences between R0, R1, and R2 resection, to describe how surgical margin status and tumor intraperitoneal rupture influence the patients' outcome, and how this may be effected by neoadjuvant and adjuvant treatment in locally advanced tumors. A systematic search of literature published between 2000 and 2018 was performed regarding this topic. Conclusion: Correct interpretation of margin status after surgery can be affected by many factors during operation and preparation of tissue.

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Laparoscopic Versus Open Resection for Gastric Gastrointestinal Stromal Tumors (GISTs): A Size–Location‐Matched Case–Control Study

Abstract: The long-term oncologic outcome of laparoscopic resection of primary gastric GISTs is comparable to that of open procedure, but laparoscopic procedure has the advantage of minimal invasion and is superior in postoperative recovery.

Cited by 23 publications

References 38 publications

Laparoscopic Partial Gastrectomy for Large Gastric GISTs

Laparoscopic Partial Gastrectomy for Large Gastric GISTs

A rare case of perivascular epithelioid cell tumor (PEComa) of the greater omentum

Is the Surgical Margin in Gastrointestinal Stromal Tumors Different

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