Trimethylamine (TMA) is an odorous volatile organic compound emitted by industries. Algalbased biotechnologies have been proven as a feasible alternative for wastewater treatment, although their application to abate polluted air emissions is still scarce. This work comparatively assessed the removal of TMA in a conventional bacterial bubble column bioreactor (BC) and a novel algal-bacterial bubble column photobioreactor (PBC). The PBC exhibited a superior TMA abatement performance compared to the conventional BC. In this sense, the BC reached a removal efficiency (RE) and an elimination capacity (EC) of 78 % and 12.1 g TMA m -3 h -1 , respectively, while the PBC achieved a RE of 97 % and a EC of 16.0 g TMA m -3 •h -1 at an empty bed residence time (EBRT) of 2 min and a TMA concentration ~500 mg m -3 . The outstanding performance of the PBC allowed to reduce the operating EBRT to 1. 5 and 1 min, while maintaining high REs of 98 and 94 %, and ECs of 21.2 and 28.1 g m -3 •h -1 , respectively. Moreover, the PBC improved the quality of the gas and liquid effluents discharged, showing a net CO2 consumption and decreasing by ~ 30 % the total nitrogen concentration in the liquid effluent via biomass assimilation. A high specialization of the bacterial community was observed in the PBC, Mumia and Aquamicrobium sp. being the mos t abundant genus within the main phyla identified.