Dengue Fever Presenting as Purtscher-like Retinopathy

Lima, Luiz H.; Vianello, Silvana; Pimentel, Sérgio Luís Gianotti; Andrade, Gabriel Costa de; Zett, Cláudio; Müller, Léo; Farah, Michel Eid; Belfort, Rubens

doi:10.1080/09273948.2017.1285036

Cited by 8 publications

(7 citation statements)

References 23 publications

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“…Our case also had features of Purtscher-like retinopathy, including cotton-wool spots, Purtscher fleckens, and compatible findings on OCT and fluorescein angiography. 6,7 In other less-recent reports of Purtscher-like retinopathy that described a hyper-reflectivity in middle and outer retinal layers in their OCT findings (before describing PAMM and AMN as distinct entities,) this hyper-reflectivity similarly resolved spontaneously after several weeks of follow-up. 8,9 This hyper-reflectivity in middle and outer retinal layers cannot be explained by cotton wool spots of Purtscher-like retinopathy, because cotton wool spots are caused by superficial retinal layers ischemia.…”

mentioning

confidence: 91%

Simultaneous paracentral acute middle maculopathy and purtscher-like retinopathy after acute febrile illness

Niyousha

Hassanpoor

Eftekhari

et al. 2018

Canadian Journal of Ophthalmology

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confidence: 91%

Simultaneous paracentral acute middle maculopathy and purtscher-like retinopathy after acute febrile illness

Niyousha

Hassanpoor

Eftekhari

et al. 2018

Canadian Journal of Ophthalmology

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“…Viral antigens recognized by cytotoxic T cells in infected monocytes elevate pro-inflammatory and vasoactive cytokine titers which lead to capillary leaking, macular edema, and its associated vascular dysfunction. 9 In our patient's SD-OCT there is a sectoral atrophy of the rod and cone layer without edema or hemorrhagic maculopathy, which points to a probable vascular dysfunction of immune etiology.…”

Section: Discussionmentioning

confidence: 49%

Acute macular neuroretinopathy associated to dengue disease

Translateur

Perez-Rueda

2022

American Journal of Ophthalmology Case Reports

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“… 146 – 149 Ophthalmologic complications have also been widely reported in association with DENV infection, including retinopathy, maculopathy, and choroiditis. 150 – 153 …”

Section: Denvmentioning

confidence: 99%

Acute neurologic emerging flaviviruses

Caldwell

Boruah

Thakur

2022

Therapeutic Advances in Infection

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The COVID-19 pandemic has shed light on the challenges we face as a global society in preventing and containing emerging and re-emerging pathogens. Multiple intersecting factors, including environmental changes, host immunological factors, and pathogen dynamics, are intimately connected to the emergence and re-emergence of communicable diseases. There is a large and expanding list of communicable diseases that can cause neurological damage, either through direct or indirect routes. Novel pathogens of neurotropic potential have been identified through advanced diagnostic techniques, including metagenomic next-generation sequencing, but there are also known pathogens which have expanded their geographic distribution to infect non-immune individuals. Factors including population growth, climate change, the increase in animal and human interface, and an increase in international travel and trade are contributing to the expansion of emerging and re-emerging pathogens. Challenges exist around antimicrobial misuse giving rise to antimicrobial-resistant infectious neurotropic organisms and increased susceptibility to infection related to the expanded use of immunomodulatory treatments. In this article, we will review key concepts around emerging and re-emerging pathogens and discuss factors associated with neurotropism and neuroinvasion. We highlight several neurotropic pathogens of interest, including West Nile virus (WNV), Zika Virus, Japanese Encephalitis Virus (JEV), and Tick-Borne Encephalitis Virus (TBEV). We emphasize neuroinfectious diseases which impact the central nervous system (CNS) and focus on flaviviruses, a group of vector-borne pathogens that have expanded globally in recent years and have proven capable of widespread outbreak.

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Dengue Fever Presenting as Purtscher-like Retinopathy

Abstract: We report two unique cases of dengue fever associated with retinal lesions in a configuration of Purtscher-like retinopathy.

Cited by 8 publications

References 23 publications

Simultaneous paracentral acute middle maculopathy and purtscher-like retinopathy after acute febrile illness

Simultaneous paracentral acute middle maculopathy and purtscher-like retinopathy after acute febrile illness

Acute macular neuroretinopathy associated to dengue disease

Acute neurologic emerging flaviviruses

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