Punch graft versus follicular hair transplantation in the treatment of stable vitiligo

Mohamed, Essam-Elden Mohamed; Younes, Abdel-Khalek Hassan; Osmand, Ahmed; Mohamed, R. A.; Makki, Mahmoud; Younis, Mahmoud

doi:10.1080/14764172.2017.1303170

Cited by 9 publications

(16 citation statements)

References 10 publications

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“…35 The most common adverse effect after PG was a cobblestone appearance, reported in up to 90% of patients. 33 Dyspigmentation (hypo-, hyper-, or depigmentation) was reported occasionally at the donor site.…”

Section: Resultsmentioning

confidence: 99%

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

McCrary

Gibbs

Alharthi

et al. 2022

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Section: Resultsmentioning

confidence: 99%

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

McCrary

Gibbs

Alharthi

et al. 2022

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“…al., 2014, 16 while Mohamed et. al., 2017, 17 used strip technique for FUT and punches of 2 mm size for mPG.…”

Section: Discussionmentioning

confidence: 99%

“…Concerning type of vitiligo, a statistically significant relation between segmental vitiligo and the response to treatment was present. Previous studies did not mention the relation between response to treatment by FUT and type of vitiligo 1,11,16,17 …”

Section: Discussionmentioning

confidence: 99%

Clinical and dermoscopic evaluation of follicular unit transplantation vs. Mini‐Punch grafting in the repigmentation of resistant and stable vitiligo: A comparative study

Mokhtar

El-Ashmawy

Mostafa

et al. 2022

J of Cosmetic Dermatology

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Background: Various surgical modalities and transplantation techniques had been evolved for the treatment of recalcitrant stable vitiligo. Each of these techniques has its own limitations and side effects. There are insufficient studies evaluating the efficacy of transplantation of hair follicle (HF) units as a surgical modality for vitiligo treatment in comparison with the classic mini-punch grafting.Objectives: To compare the efficacy and safety of follicular unit transplantation (FUT) with mini-punch grafting (mPG) in cases of resistant and stable vitiligo.Methods: Twenty-five patients with stable vitiligo were included. Treated areas were classified into 2 groups: group I: Areas were treated with the FUT technique and group II: Areas were treated with mPG technique. Treated areas were exposed to narrowband ultraviolet B phototherapy for 6 months. After 3 months, follow-up patients' response was evaluated clinically and by dermoscopy.Results: Both techniques showed efficacy in repigmentation of stable vitiligo. Group II showed a statistically significant higher percentage of repigmentation and significant earlier repigmentation than group I. Cobblestone-like appearance was the major complication in group II, while no serious side effect was reported in group I. Leukotrichia was present in 8 patients, and 6 of them showed hair repigmentation evidently in group I. Conclusion:Both techniques are effective, safe, and inexpensive methods of surgical repigmentation of stable localized/segmental vitiligo. mPG gives earlier and better percent of repigmentation, with higher incidence of cobblestoning. FUT is a good alternative for mPG, especially in hairy areas with better cosmetic outcome and minimal complications.

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“…reported that in the recipient site, cobblestone appearance was the predominant complication in mini punch grafts, whereas hyperpigmentation and thickening of grafts were common in suction blister roof grafts. Mohamed et al 20 . compared mini punch grafts and hair follicle graphs in the treatment of 32 patients with stable vitiligo, and found that the improvement of vitiligo in patients who underwent mini punch graft treatment was significantly higher than that of patients who underwent follicular hair grafts.…”

Section: Surgical Treatmentmentioning

confidence: 99%

Surgical procedures and innovative approaches for vitiligo regenerative treatment and melanocytorrhagy

Kawakami

2022

The Journal of Dermatology

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Surgical treatments for vitiligo are a safe and effective treatment modality for select patients with vitiligo. Many techniques of vitiligo surgery exist, each with unique advantages and disadvantages. We reviewed the various surgical therapies and innovative approaches for vitiligo regenerative treatment reported in the literature. Surgical therapies can be subdivided into tissue grafting methods and cellular grafting methods. Tissue grafting methods mainly include mini punch grafts, suction blister roof grafts, and hair follicle grafts. Cellular grafting methods include cultured and non-cultured treatments. The efficacy needs to be improved largely due to the poor proliferation and quality of the autologous melanocytes. Rho-associated protein kinase inhibitor enhances primary melanocyte culture proliferation from vitiligo patients to prevent apoptosis. Innovative approaches using stem cell methods could prove invaluable in developing a novel cell therapy for patients suffering from vitiligo. We succeeded in inducing melanin pigmentation in mice skin in vivo using our human induced pluripotent stem cell-derived melanocytes. In addition, we reviewed melanocytorrhagy, detachment and transepidermal loss of melanocytes, and melanocyte-related adhesion molecules. These adhesion molecules include epithelial cadherin, discoidin domain receptor tyrosine kinase 1, glycoprotein non-metastatic melanoma protein B, macrophage migration inhibiting factor, 17β-hydroxysteroid dehydrogenase 1, and E26 transformation-specific 1.

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Punch graft versus follicular hair transplantation in the treatment of stable vitiligo

Abstract: Punch grafting is more effective than follicular grafting in the treatment of stable vitiligo; however, follicular hair transplantation is cosmetically better, so we recommend it in exposed areas as face.

Cited by 9 publications

References 10 publications

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

Clinical and dermoscopic evaluation of follicular unit transplantation vs. Mini‐Punch grafting in the repigmentation of resistant and stable vitiligo: A comparative study

Surgical procedures and innovative approaches for vitiligo regenerative treatment and melanocytorrhagy

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