Pituitary tuberculoma with subsequent drug-resistant tuberculous lymphadenopathy: an uncommon presentation of a common disease

Abstract

We report a case of pituitary tuberculosis which presented as a non-functioning pituitary macroadenoma, and subsequently developed multidrug-resistant tuberculous lymphadenopathy. Pituitary tuberculosis continues to be a rare presentation of tuberculosis, but incidence and prevalence are expected to grow with increasing numbers of multidrug-resistant tuberculosis. Isolated pituitary tuberculosis is rare. Tuberculosis should be considered in the differential diagnosis in evaluation of a sellar mass.

Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report

“…Granulomatous hypophysitis is histologically differentiated from lymphocytic or xanthomatous hypohysitis by the presence of multinucleated giant cells with caseous necrosis [4]. Granulomatous hypophysitis can also occur as a secondary phenomenon due to other etiologies such as tuberculosis, sarcoidosis, syphilis, fungal infections, pituitary adenomas, Langerhans cell histiocytosis, Erdheim-Chester disease, Wegener's granulomatosis, and giant cell arteritis [2891011]. Therefore, IGH can be diagnosed after exclusion of other secondary causes.…”

A rare cause of acute hypernatraemia: Diabetes insipidus secondary to suprasellar tuberculoma

“…1,2 Suprasellar tuberculomas are much more uncommon, and often present with signs of raised intracranial pressure and optic nerve compression, as well as variable pituitary hormone deficiencies. 3 We report a unique case of suprasellar tuberculoma presenting as diabetes insipidus (DI).…”