The Global Asthma Network rationale and methods for Phase I global surveillance: prevalence, severity, management and risk factors

Ellwood, Philippa; Asher, M. Innes; Ne, Billo; Bissell, Karen; Cy, Chiang; Ellwood, Eamon; Elsony, Asma; García‐Marcos, Luis; Mallol, Javier; Marks, Guy B.; Pearce, Neil; Strachan, D P

doi:10.1183/13993003.01605-2016

Cited by 142 publications

(162 citation statements)

References 21 publications

(19 reference statements)

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“…Some factors have been explored in ISAAC and GAN, such as changes in diet, time spent using screens (computers and video games), second-hand smoke, and the presence of pollutants. 10,20 In the present study, possible risk factors identified for WHEZEV and WHEZ12 were the presence of other allergic diseases (hay fever and eczema), early infections, smoking at home, and paracetamol use. These patterns have been described previously; for example, the evolution of allergic sensitization followed by atopic dermatitis, allergic rhinitis, and asthma have been demonstrated in several epidemiological studies.…”

Section: Discussionmentioning

confidence: 56%

“…After providing informed consent, parents completed validated and standardized questionnaires given by GAN's global coordination for the younger group, and the older group completed the questionnaires by themselves. 10 Following the official GAN protocol, 10 the sample unit was the whole population of children aged 6-7 years or adolescents aged 13-14 years in a given school. The schools were within a certain geographical radius of the study centre and were chosen randomly based on the school register (organized in alphabetical order).…”

Section: Methodsmentioning

confidence: 99%

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The burden of asthma in an inner-city area: A historical review 10 years after ISAAC

Del-Río-Navarro

Navarrete-Rodríguez

Berber

et al. 2020

World Allergy Organization Journal

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Background: According to the International Study of Asthma and Allergies in Childhood (ISAAC) methodology, in 2003, the prevalence of asthma symptoms in children 6-7 years old and adolescents 13-14 years old was 11.6% and 13.7%, respectively. Since then, the number of asthma cases has increased worldwide. The study was conducted in several districts in northern Mexico City to evaluate the prevalence of asthma in these age groups and examine possible risk factors. The data were compared to the 2003 results from the same area. Methods: This was a comparative cross-sectional study following the official Global Asthma Network (GAN) methodology. The parents or guardians of participants completed a questionnaire that explored demographics, asthma symptoms, diagnoses, and possible risk factors. Central tendency measurements were determined for statistical analysis and chi-squared distribution for possible risk factors. Results: A total of 2515 children aged 6-7 years and 3375 adolescents aged 13-14 years participated in the study. Compared to the ISAAC results, we found a greater prevalence of wheezing in both children (at some time in life, 19.2% vs. 27.1%; over the last year, 6.8% vs. 10.6%) and adolescents (at some time in life, 16.9% vs. 19.7%), and for children with an asthma diagnosis (4.5% vs. 5.1%). For both groups, the most common risk factor associated with wheezing was the presence of rhinitis symptoms. Conclusions: Asthma symptoms are highly prevalent in Mexico City, occurring in almost 20% of adolescents. Compared to a decade ago, there was a 7.9% increase in the prevalence of asthma symptoms in children. Almost half of the children and adolescents presenting with symptoms had experienced more than four episodes per year. However, less than 50% of children and adolescents with asthma symptoms had been diagnosed with this disorder, suggesting under-diagnosis.

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Section: Discussionmentioning

confidence: 56%

Section: Methodsmentioning

confidence: 99%

The burden of asthma in an inner-city area: A historical review 10 years after ISAAC

Del-Río-Navarro

Navarrete-Rodríguez

Berber

et al. 2020

World Allergy Organization Journal

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show abstract

“…Asthma is one of the most common chronic diseases in childhood and is considered an important public health problem which leads to impairment of the quality of life (14,15) . Its main characteristic is inflammation of the airways, which leads to a condition of hyperreactivity to allergenic exposure and inhalation of irritants, or triggered by physical exercise (2) .…”

Section: Resultsmentioning

confidence: 99%

Evidence of orofacial myofunctional therapy patients with asthma and rhinitis: a systematic review

Araújo

Simões

Moreira

et al. 2019

CoDAS

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Purpose to evaluate the efficacy of orofacial myofunctional therapy in improving orofacial function and nasal breathing in patients with asthma and rhinitis and, consequently, achieve clinical control of these conditions. Research strategies We used the elements of the PICOT method (study population, intervention, comparison, outcomes and type of studies) to define the eligibility criteria: (1) Population: patients with asthma and rhinitis; (2) Intervention: orofacial myofunctional therapy to improve chewing, swallowing, and breathing; (3) Comparison: control group without orofacial myofunctional therapy; (4) Predefined outcomes: clinical control of asthma and improvement of orofacial functions and nasal breathing; (5) Study type: clinical trials. The data were collected from PubMed, SCOPUS, Web of Science, Science Direct, LILACS, Google Scholar, Cochrane Central Register of Controlled Trials (CENTRAL), OATD, and Open Thesis, in November 2018. Selection criteria Randomized controlled trials published in full-text versions without language restriction, no filter was used. Data analysis Demographic characteristics of study participants, specific diagnosis of asthma and control medication, type, duration, intensity and follow-up of orofacial myofunctional therapy, and outcome data. The risk of bias was assessed according to the Cochrane guidelines for clinical trials. Results One study met the eligibility criteria: although the study has shown an improvement of functional control and clinical scores of asthma, the evidence is very low. Conclusion There is no scientific evidence on the efficacy of orofacial myofunctional therapy in improving clinical control, orofacial function, and nasal breathing in patients with asthma and rhinitis.

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“…Asthma is a common chronic disease with 1 in 9 Australians diagnosed with the illness (AIHW, 2019). Globally, around 241 million people are living with asthma (Ellwood et al, 2017). Asthma is often treated with inhalational corticosteroids, which have been linked to increased rates of oral candidosis in those patients (Ellepola & Samaranayake, 2001; Kennedy et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

Chronic disease comorbidity in patients with oral leukoplakia: A matched case–control study

et al. 2020

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Objective The purpose of this study was to investigate the presence of chronic diseases in patients with oral leukoplakia (OL) compared to controls matched for age group, gender, smoking and alcohol use. Subjects and Methods This case–control study examined the general demographics, medical and social histories of 105 OL cases and 391 controls matched for age group, gender, tobacco and alcohol use. All OL cases were diagnosed based on both clinical and histopathological findings. Results Chronic diseases were significantly associated with OL, namely dyslipidaemia (p < .0001), musculoskeletal diseases (p = .0101) and asthma (p = .0052). The use of ACE inhibitors (p = .0177), opioid analgesics (p = .0300), anticoagulants (p = .0055) and statins (p = .0010) was significantly associated with OL. Dyslipidaemia (p < .0001; odds ratio [95% CI]: 6.4 [3.5–11.6]) and asthma (p = .0110; odds ratio [95% CI]: 2.2 [1.2–4.0]) were identified as independent predictors of OL in multivariate analysis, both of which were significantly more common amongst cases than controls. Conclusions Results from this first Australian study suggest that dyslipidaemia and asthma may constitute independent predictors for the presence of OL. However, longitudinal studies are needed to ascertain the temporal relationship between OL and chronic disease comorbidity and the mechanisms underlying these associations.

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The Global Asthma Network rationale and methods for Phase I global surveillance: prevalence, severity, management and risk factors

Cited by 142 publications

References 21 publications

The burden of asthma in an inner-city area: A historical review 10 years after ISAAC

The burden of asthma in an inner-city area: A historical review 10 years after ISAAC

Evidence of orofacial myofunctional therapy patients with asthma and rhinitis: a systematic review

Chronic disease comorbidity in patients with oral leukoplakia: A matched case–control study

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