Primary Intracranial Malignant Melanoma with Extracranial Metastasis

Abstract

We report a case of primary intracranial malignant melanoma (PIMM) with extracranial metastases. The patient was an 82-year-old woman diagnosed with PIMM under the left cerebellar tentorium. We performed a tumor resection followed by gamma knife surgery. An magnetic resonance imaging at 11 months after surgery showed a local intracranial recurrence. At 12 months, vertebral metastasis was suspected, and 2-[fluorine-18]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) showed multiple extracranial metastases. She died at 13 months after surgery. Although extracranial metastases of PIMM are extremely rare, we should carefully follow up extracranial metastases together with intracranial ones, especially by FDG-PET/CT, even at an early asymptomatic stage.

Atypical Melanoma Misdiagnosed as Viral Meningoencephalitis: A Case Report

“…The melanocytic tumors of central nervous system tumors are divided into meningeal melanocytosis, meningeal melanocytoma, meningeal melanoma and meningeal melanomatosis, of which the latter two are classified as malignant lesions [1]. CNS melanoma tumors are mostly transferred from other systems and ranks third among the most common brain metastases tumors [2]. Melanoma originated from the CNS is very rare, accounting for only 1% of all melanomas, 0.07% of brain tumors [3][4][5], and CNS melanoma can be transferred to other sites.…”