Diagnosis and treatment of epidural metastases

Yáñez, M. Loreto; Miller, Julie; Batchelor, Tracy T.

doi:10.1002/cncr.30521

Cited by 31 publications

(23 citation statements)

References 35 publications

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“…Additional causes include coagulopathy, trauma, and iatrogenic causes from interventional pain management procedures. Intratumoral hemorrhage within epidural spread of tumor can also result in epidural hematoma (16).…”

Section: Epidural Hematoma Backgroundmentioning

confidence: 99%

“…Epidural Tumor Spread and Metastasis.-Epidural tumor from metastases or other causes may hemorrhage (19). It has been reported that 5%-10% of cancer patients will develop metastatic disease in this region (16). The most frequently reported causes of epidural metastasis include breast, lung, and prostate cancers.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…The most frequently reported causes of epidural metastasis include breast, lung, and prostate cancers. Epidural tumor typically shows T1 signal hypointensity to the spinal cord, variable T2 signal intensity, and more solid postcontrast enhancement (16) (Fig 6). Nonenhancement due to tumor necrosis may also be encountered.…”

Section: Differential Diagnosismentioning

confidence: 99%

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Spinal Hematomas: What a Radiologist Needs to Know

et al. 2018

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Spinal hematomas are a frequent indication for radiologic evaluation and can be a diagnostic dilemma for many radiologists and surgeons. There are four types of spinal hematomas: epidural, subdural, subarachnoid, and intramedullary (spinal cord) hematomas. Because they differ by their location in relationship to the meningeal membranes and spinal cord, unique radiologic appearances can be recognized to distinguish these types of spinal hemorrhage. Anatomic knowledge of the spinal compartments is essential to the radiologist for confident imaging diagnosis of spinal hematomas and to specify correct locations. MRI is the modality of choice to diagnose the location of the hematoma, characterize important features such as age of the hemorrhage, and detect associated injury or disease. Each type of spinal hematoma has imaging patterns and characteristics that distinguish it from the others, as these specific spinal compartments displace and affect the adjacent anatomic structures. Early detection and accurate localization of spinal hematomas is critical for the surgeon to address the proper treatment and surgical decompression, when necessary, as neurologic deficits may otherwise become permanent. Online supplemental material is available for this article. RSNA, 2018.

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Section: Epidural Hematoma Backgroundmentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

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Spinal Hematomas: What a Radiologist Needs to Know

et al. 2018

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“…Azoknak a betegeknek, akik jól reagáltak a sugárterápiára, relapsus esetén újabb besugárzást lehet alkalmazni. A dekompressziós laminectomiát elsősorban azokban az esetekben kell elvégezni, amikor a neurológiai tünetek súlyosak (hólyag-és bélműködési zavar) vagy gyorsan romlanak, illetve ha progressziót észlelünk a szteroidkezelés és radioterápia ellenére (sugárrezisztens tumorok) [11].…”

Section: Gerincvelő-kompresszióunclassified

Szteroidok szerepe az onkológiai gyakorlatban

et al. 2017

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Corticosteroids are a class of steroid hormones that are produced and disengage in the adrenal cortex. Traditionally natural and synthetic corticosteroids are used for diagnosing and treating dysfunctions of the adrenal cortex and treating inflammatory and immunological diseases. Their use is also widespread in oncological practice. Corticosteroids are indispensable in palliative care, in certain urgent oncological cases, as premedication of some chemotherapies and last but not least they have a key role in the secondary hormonal manipulations of metastatic castrate-resistant prostate cancer. The purpose of our review is to describe and compare the effects of different agents in oncological practice, to give a detailed account of the above mentioned indications and would also like to draw attention to the possible side effects of a long-term steroid treatment. Orv Hetil. 2017; 158(42): 1651-1657.

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“…An estimated 30-40% of patients with disseminated cancer have a spinal metastasis and about 10% of these patients need surgical treatment due to metastatic epidural spinal cord compression (MESCC) [2,3]. The risk of MESCC within 5 years before the patient's death is estimated at 2.5% [4].…”

Section: Introductionmentioning

confidence: 99%

Predictor of neurological function after surgical treatment of the metastatic epidural spinal cord compression

Adamski¹

2018

Chir. Narzadow Ruchu Ortop. Pol.

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Introduction. Postoperative neurological function influent prognosis and quality of life among patients with metastatic epidural spinal cord compression (MESCC). Aim. The aim of this study was to assess the predictor of postoperative neurological function in patients with MESCC, treated with spinal cord decompression. Materials and methods. The study analysed the medical records of 51 patients who underwent surgical treatment with corpectomy at the Department of Oncological Orthopaedics in Brzozów in 2014-2015. The majority of patients were male (61%). The mean age of patients was 61 years. Influence of following variable on postoperative neurological function were assessed: age, gender, location of primary tumor, location and number of affected segments, the pre-and early postoperative Frankel grade, ability to walk and use of walking aid. Variables were analyzed with univariate methods. Results. The majority of the patients were assigned to Frankel grade C. After surgical intervention 68 % of patients reagin ability to walk. Univariate analyses identify preoperative impairment scale grades, the ability to walk preoperatively, tumor localization, as predictors for neurological improvement and outcome. Conclusions. Early surgical decompression is essential to preserve neurological function, especially for patients with myeloma.

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Diagnosis and treatment of epidural metastases

Cited by 31 publications

References 35 publications

Spinal Hematomas: What a Radiologist Needs to Know

Spinal Hematomas: What a Radiologist Needs to Know

Szteroidok szerepe az onkológiai gyakorlatban

Predictor of neurological function after surgical treatment of the metastatic epidural spinal cord compression

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