Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation

Dezfuli, Sina Naddaf; Leeflang, M.A.; Huan, Zhiguang; Chang, Jiang; Zhou, Jie

doi:10.1016/j.jmbbm.2016.10.010

Cited by 28 publications

(23 citation statements)

References 46 publications

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“…Moreover, further in vivo study [123] illustrated that the HA-Ti biocermets possessed appropriate histocompatibility and osteogenesis. Dezfuli et al [124] prepared Mg-bredigite biocermets by sintering at 150-350 °C for 1-4 h under a pressure of 500 MPa and found that the biocermets had lower degradation rates and better mechanical properties than Mg. During degradation, the mechanical properties of the biocermets gradually decreased, but the ultimate compressive strength was still comparable with that of cortical bone after 12 days' degradation.…”

Section: Hot Pressingmentioning

confidence: 99%

Advances in biocermets for bone implant applications

et al. 2020

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As two promising biomaterials for bone implants, biomedical metals have favorable mechanical properties and good machinability but lack of bioactivity; while bioceramics are known for good biocompatibility or even bioactivity but limited by their high brittleness. Biocermets, a kind of composites composing of bioceramics and biomedical metals, have been developed as an effective solution by combining their complementary advantages. This paper focused on the recently studied biocermets for bone implant applications. Concretely, biocermets were divided into ceramic-based biocermets and metal-based biocermets according to the phase percentages. Their characteristics were systematically summarized, and the fabrication methods for biocermets were reviewed and compared. Emphases were put on the interactions between bioceramics and biomedical metals, as well as the performance improvement mechanisms. More importantly, the main methods for the interfacial reinforcing were summarized, and the corresponding interfacial reinforcing mechanisms were discussed. In addition, the in vitro and in vivo biological performances of biocermets were also reviewed. Finally, future research directions were proposed on the advancement in component design, interfacial reinforcing and forming mechanisms for the fabrication of high-performance biocermets.

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Section: Hot Pressingmentioning

confidence: 99%

Advances in biocermets for bone implant applications

et al. 2020

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“…As a result, the refined grain size, together with the dissolved Pd and dispersed Pd-rich IMPs, contributed to the improvement of CYS by immobilizing dislocations and thus inducing more deformation resistance. In comparison, bredigite showed a negative influence on CYS, which be due to the microstructure inhomogeneity, such as interfacial mismatch and different deformation mechanisms between metals and ceramics [48]. Nevertheless, the microhardness of the biocomposites was improved after the addition of bredigite, which could be ascribed to the uniform distribution of the hard bredigite phase within the matrix.…”

Section: Discussionmentioning

confidence: 93%

Highly biodegradable and bioactive Fe-Pd-bredigite biocomposites prepared by selective laser melting

Gao

Yang

et al. 2019

Journal of Advanced Research

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“…Figure 11 shows comparisons of strength retention of Mg-based composites [38,39,51]. Strength retention was calculated by dividing the strength change by the initial ultimate compressive strength before degradation for ultimate compressive strength.…”

Section: Deterioration Of Strength Due To Degradation In a Physiological Saline Solutionmentioning

confidence: 99%

“…Fewer studies addressed the mechanical integrity of Mg-based materials compared with ones focusing on the corrosion resistance and initial mechanical properties [10,[35][36][37][38]. Jie Zhou's group showed that incorporating 20 vol% bredigite particles into the Mg matrix by pressure-assisted sintering improved mechanical integrity upon the immersion in a cell culture medium compared with monolithic Mg [39]. They showed that corrosion pits acted as nucleation sites of mechanical cracks for Mg/bredigite composites.…”

Section: Introductionmentioning

confidence: 99%

Effects of Incorporating Β-Tricalcium Phosphate with Reaction Sintering into Mg-Based Composites on Degradation and Mechanical Integrity

Narita

Hiromoto

Kobayashi

et al. 2021

Metals

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For applications of biodegradable load-bearing implants, we incorporated 10 or 20 vol% β-tricalcium phosphate (β-TCP) into Mg-based composites through reaction sintering in the spark plasma sintering process. We previously reported that the evolved microstructure enhanced mechanical properties before degradation and modified in vitro degradation behaviors. In this study, immersion tests in physiological saline and subsequent compression tests in the air were conducted to investigate the effects of degradation on mechanical integrity. In the immersion tests, Mg/β-TCP composites showed no visible disintegration of sintered particles due to interfacial strength enhanced by reaction sintering. Local corrosion was observed in the Mg matrix adjacent to the reaction products. In addition, Mg/10% β-TCP showed dense degradation products of Mg(OH)2 compared with Mg and Mg/20% β-TCP. Those degradation behaviors resulted in reducing the effective load transfer from the Mg matrix to the reaction products as reinforcement. The yield strength decreased by 18.1% for Mg/10% β-TCP and 70.9% for Mg/20% β-TCP after six days of immersion. These results can give a broad view of designing spark plasma sintered Mg/bioceramic composites with the consideration of mechanical integrity.

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Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation

Cited by 28 publications

References 46 publications

Advances in biocermets for bone implant applications

Advances in biocermets for bone implant applications

Highly biodegradable and bioactive Fe-Pd-bredigite biocomposites prepared by selective laser melting

Effects of Incorporating Β-Tricalcium Phosphate with Reaction Sintering into Mg-Based Composites on Degradation and Mechanical Integrity

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