Protein capped Cu nanoclusters-SWCNT nanocomposite as a novel candidate of high performance platform for organophosphates enzymeless biosensor

Bagheri, Hasan; Afkhami, Abbas; Khoshsafar, Hosein; Hajian, Ali; Shahriyari, Alireza

doi:10.1016/j.bios.2016.10.003

Cited by 101 publications

(39 citation statements)

References 45 publications

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“…Finally, we outline current challenges and our perspective on the development of CuNCs.When decreasing the size of nanoparticles so that it approaches the Fermi wavelength of an electron, novel optical, electrical and magnetic properties appear (Deng et al 2018a; Li et al 2016b;Moghadam and Rahaie 2019;Wang et al 2018c). Commonly termed nanoclusters (NCs), these ultra-small nanoparticles, bridging the missing link between atoms and nanocrystals, have attracted considerable attention in both fundamental research and practical applications (Bagheri et al 2017;Basu et al 2019;Sun et al 2019;Wang et al 2016b). Benefiting from the great progress in nanosynthetic chemistry, high-quality Copper NCs (CuNCs) with tailored size and good stability can be easily obtained.…”

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confidence: 99%

Highly fluorescent copper nanoclusters for sensing and bioimaging

Ren

Bick

et al. 2020

Biosensors and Bioelectronics

147

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Metal nanoclusters (NCs), typically consisting of a few to tens of metal atoms, bridge the gap between organometallic compounds and crystalline metal nanoparticles. As their size approaches the Fermi wavelength of electrons, metal NCs exhibit discrete energy levels, which in turn results in the emergence of intriguing physical and chemical (or physicochemical) properties, especially strong fluorescence. In the past few decades, dramatic growth has been witnessed in the development of different types of noble metal NCs (mainly AuNCs and AgNCs). However, compared with noble metals, copper is a relatively earth-abundant and cost-effective metal. Theoretical and experimental studies have shown that copper NCs (CuNCs) possess unique catalytic and photoluminescent properties. In this context, CuNCs are emerging as a new class of nontoxic, economic, and effective phosphors and catalysts, drawing significant interest across the life and medical sciences. To highlight these achievements, this review begins by providing an overview of a multitude of factors that play central roles in the fluorescence of CuNCs. Additionally, a critical perspective of how the aggregation of CuNCs can efficiently improve the florescent stability, tunability, and intensity is also discussed. Following, we present representative applications of CuNCs in detection and bioimaging. Finally, we outline current challenges and our perspective on the development of CuNCs.When decreasing the size of nanoparticles so that it approaches the Fermi wavelength of an electron, novel optical, electrical and magnetic properties appear (Deng et al. 2018a; Li et al. 2016b;Moghadam and Rahaie 2019;Wang et al. 2018c). Commonly termed nanoclusters (NCs), these ultra-small nanoparticles, bridging the missing link between atoms and nanocrystals, have attracted considerable attention in both fundamental research and practical applications (Bagheri et al. 2017;Basu et al. 2019;Sun et al. 2019;Wang et al. 2016b). Benefiting from the great progress in nanosynthetic chemistry, high-quality Copper NCs (CuNCs) with tailored size and good stability can be easily obtained. CuNCs, therefore, constitute an active research direction due to their unique properties, such as high luminous efficiency, long fluorescence lifetime, good optical and chemical stability, and large stokes displacement, which distinguish them as a new type of fluorescent probe for optical sensing and bioimaging/labeling (Cao et al. 2014;Wang et al. 2017).In this review, we highlight recent developments of CuNCs, with a particular emphasis on the multiple factors affecting fluorescent properties of CuNCs, as well as the aggregation-induced emission enhancement (AIEE) effect. To appreciate these advances, applications focused on the detection of ions, macromolecules and bioimaging are summarized. Lastly, we will provide a brief conclusion, and will address future challenges in the rapidly growing field of fluorescent CuNCs. Multiple factors that govern the fluorescence of CuNCsDue to the size of CuNCs falls w...

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confidence: 99%

Highly fluorescent copper nanoclusters for sensing and bioimaging

Ren

Bick

et al. 2020

Biosensors and Bioelectronics

147

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“…For this reason, this polymerization condition was chosen for the application studies of the nanohybrid electrode. Electroactive surface areas for the nanohybrid electrode and polypyrrole electrode were calculated based on the I pa values . They were found as 18.7±0.4 and 18.5±0.5, respectively.…”

Section: Resultsmentioning

confidence: 99%

Polypyrrole‐Based Nanohybrid Electrodes: Their Preparation and Potential Use for DNA Recognition and Paclitaxel Quantification

Kuralay

Dükar

2020

ChemistrySelect

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Fabrication of conducting polymer networks based on polypyrrole/multi-walled carbon nanotubes (PPy/MWCNTs) modified graphite electrodes that were achieved with a single-step electropolymerization and potential use of these electrodes for deoxyribonucleic acid (DNA) recognition and anticancer drug (Paclitaxel, PTX) quantification were presented in the present work. PPy/MWCNTs nanohybrid PGEs were constructed in aqueous solution of pyrrole (Py) and MWCNTs using cyclic voltammetry (CV) and constant potential electrolysis. Soformed electrodes were characterized with cyclic voltammetry and electrochemical impedance spectroscopy (EIS). Surface morphologies of the surfaces were investigated by scanning electron microscopy (SEM) studies. Bio-application of the PPy/ MWCNTs nanohybrid modified PGEs were accomplished by subjecting them to double-stranded DNA (dsDNA) modification for direct DNA recognition and PTX determination. For the drug determination, interaction of DNA-based electrodes with PTX was investigated. Detection limit was found as 1.55 x 10 À 8 M based on the changes in the oxidation of guanine base which made the proposed electrode convenient for clinical trials.

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“…As a powerful technique for probing the features of electrode surface, the EIS was applied to investigate the interfacial properties of electrode surface within the stepwise modication process. [34][35][36] . As it can be seen, signicant changes in the impedance data were obtained at bare GCE, PMel/GCE* and PMel-Au nano /GCE*.…”

Section: Eis Studiesmentioning

confidence: 99%