Giant Condyloma (Buschke-Loewenstein Tumor) in a 16-year-old Patient: Case Report

Abstract

The Buschke-Loewenstein tumor is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region. It is considered benign despite the high rate of recurrence and the possibility of malignant transformation. It is commonly associated with subtypes 6 and 11 of the human papillomavirus (HPV), and host's immunity plays an important role in the development of the disease. Surgical excision is the recommended treatment in most cases. We present the case of a 16 years old female patient with extensive vulvar lesions successfully treated surgically.

Giant Vulvar Condylomata: Two Cases and a Review of the Literature

“…Buschke-Loewenstein tumor is a sexually transmitted disease caused by HPV subtypes 6 and 11, with benign histological features, but with excessive local growth and high recurrence rates [4]. They may rarely be associated with high-risk HPV types such as HPV type 16 [5].…”

“…They may rarely be associated with high-risk HPV types such as HPV type 16 [5]. Main site of appearance is the vulva in women and it is almost always preceded by condyloma acuminate [4]. The overgrowth results in hygienic problems, increases the risk of secondary infections, and distorts the genital image, which leads to social and psychological damage.…”

“…Petrini et al reported a case of a 16-year-old patient with alcohol consumption and illicit drug usage [4]. The authors linked the appearance of the disease in this young patient with associated immunosuppression.…”

“…Giant vulvar condyloma, also called Buschke-Löwenstein tumor, was first described by Abraham Buschke and Loewenstein Ludwig in 1925 [3]. Giant condyloma is usually associated with the HPV subtypes 6 and 11 and is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region and is considered benign with high rate of recurrence and low risk of malignant transformation [4]. Host's immunity plays an important role in the development of the disease.…”

Possibility of reconstruction after surgical treatment for giant Buschke–Löwenstein condyloma

“…[15]. Основным местом появления опухоли Бушке-Лёвенштейна у женщин является вульва, и ей почти всегда предшествует остроконечная кондилома [16]. Чрезмерный рост приводит к проблемам с гигиеной, увеличивает риск вторичных инфекций и искажает образ половых органов, что приводит к социальному и психологическому ущербу.…”