Symptomatic and presumed symptomatic focal epilepsies in childhood: An observational, prospective multicentre study

Vecchi, Marilena; Barba, Carmen; Carlo, Debora De; Stivala, Micol; Guerrini, Renzo; Albamonte, Emilio; Ranalli, Domiziana; Battaglia, Domenica; Lunardi, G.; Boniver, Clementina; Piccolo, Benedetta; Pisani, Francesco; Cantalupo, Gaetano; Nieddu, G.; Casellato, Susanna; Cappanera, Silvia; Cesaroni, Elisabetta; Zamponi, Nelia; Serino, Domenico; Fusco, Lucia; Iodice, Alessandro; Palestra, Filippo; Giordano, Lucio; Freri, Elena; Giorgi, I.; Ragona, Francesca; Granata, Tiziana; Fiocchi, Isabella; Bova, Stefania Maria; Mastrangelo, Massimo; Verrotti, Alberto; Matricardi, Sara; Fontana, Elena; Caputo, Davide; Darra, Francesca; Bernardina, Bernardo Dalla; Beccaria, Francesca; Capovilla, Giuseppe; Baglietto, M. P.; Gagliardi, Alessandra; Canevini, Maria Paola; Perissinotto, Egle; Francione, Stefano

doi:10.1111/epi.13574

Cited by 9 publications

(2 citation statements)

References 38 publications

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“…Thus, more alterations of metabolic network in TLE patients with HS could produce a decrease of AED response. Furthermore, when investigating neuroimaging and cognitive function in patients with newly diagnosed focal epilepsy, patients with an abnormal MRI usually have a higher chance of abnormal cognition than those with a normal MRI ( Vecchi et al, 2016 ). We can assume that the higher decrease of AED response and cognitive impairments seen in patients with TLE with HS compared to those without HS might be related to more disruptions of metabolic connectivity.…”

Section: Discussionmentioning

confidence: 99%

Alterations in the metabolic networks of temporal lobe epilepsy patients: A graph theoretical analysis using FDG-PET

Shim

Lee

Kim

et al. 2020

NeuroImage: Clinical

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Section: Discussionmentioning

confidence: 99%

Alterations in the metabolic networks of temporal lobe epilepsy patients: A graph theoretical analysis using FDG-PET

Shim

Lee

Kim

et al. 2020

NeuroImage: Clinical

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“…This has been done in our series. Conversely, these causes are reported at fairly high rates in the series using brain MRI [27, 28]. Structural damage such as cortical necrosis with HSV1, infarction with meningitis, hypoxo-ischemic lesions in the CM, and gliosis around neurocysticercosis calcifications can all constitute epileptogenic foci.…”

Section: Discussionmentioning

confidence: 99%

Etiologies of non-genetic epilepsies of child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso

Lompo¹,

Ousseini²,

Dao³

et al. 2018

Pan Afr Med J

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Introduction in sub-Saharan Africa, epilepsy is common and mainly concerns children before the age of 15 years. The data on childhood epilepsy is parcel, but a high prevalence of non-genetic epilepsy is frequently reported. EEG, TDM and MRI devices are rare. The aim of this work was to study the etiological aspects of non - genetic epilepsy of the child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso. Methods This was a cross-sectional, descriptive, multicentric study, from 01/01/2016 to 31/12/2016, involving patients aged 0 to 18 years old, epileptic, newly diagnosed, in the city of Ouagadougou. Each patient included in the study was to have had an EEG and brain CT scan and/or brain MRI and to gather the anamnestic and electro clinical arguments for non-genetic epilepsy. Sociodemographic, clinical, EEG and neuroradiological data were analyzed. An univariate analysis was used to determine the electro-clinical and neuro-radiological characteristics associated with epilepsies of structural causes. Results In all 115 patients were collected, with an average age of onset of epilepsy of 8.2 years, a male predominance with a sex ratio to 1.67. Risk factors of epilepsy was present in 74.8%; They were dominated by perinatal events in 79.1%. Focal seizures, daily frequency of these seizures and focal epilepsy, were predominant, respectively in 53%, 58% and 60.9% of cases. Brain scan and Brain MRI where performed in 90.4% and 9.6% of patients, respectively. The brain sequelaes of perinatal adverse events, the sequelae of central nervous system infections, and the sequelae of cranial and brain trauma, with 34.8%, 14.8%, and 5.2% respectively, were the main causes of non- genetic epilepsies of the child and adolescent. No cause was identified in 37.4% of cases. Conclusion The improvement of policies in the field of maternal and child health and the generalization of the control of infectious and parasitic diseases, including malaria, may contribute to the reduction of non-genetic epilepsy in sub-Saharan Africa.

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EEG for children with complex febrile seizures

Shah

James

Elayaraja

2017

Cochrane Database of Systematic Reviews

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We attempted to search all possible sources but were unable to find any randomised controlled trials to address the issue up to 23 January 2017. We concluded that there is no high-quality evidence to support or refute the use of an EEG and its timing a er complex febrile seizures in children. Well-designed randomised controlled trials are therefore required. We intend to update this review regularly with the hope that new randomised studies will be reported in the future. EEG for children with complex febrile seizures (Review)

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Symptomatic and presumed symptomatic focal epilepsies in childhood: An observational, prospective multicentre study

Abstract: In this prospective cohort study, an extensive characterization of epilepsy onset in children with symptomatic or presumed symptomatic focal epilepsies is reported in relation to the age group and the localization of the epileptogenic zone.

Cited by 9 publications

References 38 publications

Alterations in the metabolic networks of temporal lobe epilepsy patients: A graph theoretical analysis using FDG-PET

Alterations in the metabolic networks of temporal lobe epilepsy patients: A graph theoretical analysis using FDG-PET

Etiologies of non-genetic epilepsies of child and adolescent, newly diagnosed in Ouagadougou, Burkina Faso

EEG for children with complex febrile seizures

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