“…Person-years were calculated from the date the baseline questionnaire was completed to first hospital record of any stroke (ICD codes I60–I64), death, emigration, or March 31, 2015 (the latest date when complete information was available), whichever was earliest. Time in study was the underlying time variable, and analyses were stratified by year of birth (1930 or before, 1931 to 1949 in single years, 1950 or later) and of completion of the baseline questionnaire (2000 or before, 2001, 2002, 2003, 2004 or later) and adjusted for region of residence (10 geographical areas in the United Kingdom), socioeconomic status (5 levels of the Townsend index 10 ), educational attainment (tertiary, secondary/technical, no formal qualifications 11 ), and when appropriate for smoking (never, past, current <5, 5–9, 10–14, 15–19, 20–24, ≥25 cigarettes/d), alcohol consumption (none, ≤6, 7–14, ≥15 drinks/wk), body mass index (<25, 25–29.9, ≥30 kg/m 2 ), physical activity (thirds of excess metabolic equivalents), and menopausal hormone therapy (never, past, current). For adjustment variables, missing values were assigned to an unknown category and represented <5% of the data in every variable.…”