Preoperative predictors of delay in initiation of adjuvant chemotherapy in patients undergoing primary debulking surgery for ovarian cancer

Predictive Factors for Surgical Morbidities and Adjuvant Chemotherapy Delay for Advanced Ovarian Cancer Patients Treated by Primary Debulking Surgery or Interval Debulking Surgery

“…Also, in the study by Singh et al, 23 PFS was significantly higher for patients with no ACD when compared with patients with delay. Our results show a relationship between ACD with lower PFS only in the PDS group; the same does not occur in the IDS group.…”

“…It was considered ACD when more than 42 days elapsed between the date of surgery and the initiation of adjuvance, or when the patient did not receive chemotherapy. 19,23 To evaluate the degree of surgical complexity, Aletti score was used. 24 In this complexity classification system, scores of 3 or lower determine low complexity, scores between 4 and 7 denote intermediate complexity, and scores of 8 or higher denote high surgical complexity.…”

Predictive and Prognostic Implication of Bowel Resections During Primary Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer

“…The prolonged postoperative recovery resulted in a longer time interval to the start of chemotherapy, which had been reported to be an independent factor of decreased OS in EOC. 11,15,16 The present study faced a number of limitations. First, diagnosis of AL was not based on routine postinterventional screenings, but diagnostics for AL were initiated only if severe abdominal complications were suspected.…”

Impact of interval from primary cytoreductive surgery to initiation of adjuvant chemotherapy in advanced epithelial ovarian cancer

“…Complications, medical co‐morbidities, and Eastern Cooperative Oncology Group scores might have influenced the interval between surgery and chemotherapy; however, these data were not taken into account in the analysis. Moreover, different medical systems have various health system logistics for referrals and wait times that may have affected the treatment interval . A strength of the study is the large cohort.…”