Functionalized poly (ionic liquid) as the support to construct a ratiometric electrochemical biosensor for the selective determination of copper ions in AD rats

Yu, Yanyan; Yu, Chao; Yin, Tianxiao; Ou, Shanshan; Sun, Xiaoyu; Wen, Xiangru; Zhang, Lin; Tang, Daoquan; Yin, Xiaoxing

doi:10.1016/j.bios.2016.08.066

Cited by 47 publications

(24 citation statements)

References 40 publications

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“…The electrochemical sensing strategies published in the last five years for Cu 2+ monitoring offer examples of most of the bio-and biomimetic recognition layers previously presented (Section 2): from peptides, to DNAzymes and imprinted polymers-based ones. In 2016, Yu et al [76] reported a Very recently the performances of Hg 2+ electrochemical biosensors have been further improved also by designing new amplification strategies and combing these bioreceptors with various nanoand nanocomposite materials [116], from gold nanorods functionalized with graphene oxide [64] to porous silicon nanowires [65]. For instance, Jin et al employed a T-rich thiolated DNA (S1), which was self-assembled on a gold electrode, and a T-rich biotin-DNA (biotin-S2) to capture Hg 2+ in water through T-Hg-T complex formation, thus leading to a sandwich-like biosensing platform [64].…”

Section: Coppermentioning

confidence: 99%

“…wastewater certified reference material (ERMs-CA71) [75] DHF-PIL-ABTS/NKB/Glu 0.9-36.1 µM LOD 0.24 µM LOQ 0.6 µM cerebrospinal fluid hippocampus [76] Neurokinin B (NKB) ABTS-PDDA/CNTs-NKB 0.1-10 µM 0.04 µM plasma hippocampus [77] Oxytocin (OT) -500 fM healthy and MS sera patients [78] Oxytocin (OT) 10 −13 -10 −9 M -- [79] Cuzyme/SWNTs/FET 0,01-10,000 nM 0.0064 nM pait, soil [68] 3DOM CS-PB-SWCNTs Glutathione modified SPE with carbon nanofiber electrode (GSH-SPCNFE)…”

Section: Imprinted Polymersmentioning

confidence: 99%

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Bio- and Biomimetic Receptors for Electrochemical Sensing of Heavy Metal Ions

Stortini

Baldo

Moro

et al. 2020

Sensors

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Heavy metals ions (HMI), if not properly handled, used and disposed, are a hazard for the ecosystem and pose serious risks for human health. They are counted among the most common environmental pollutants, mainly originating from anthropogenic sources, such as agricultural, industrial and/or domestic effluents, atmospheric emissions, etc. To face this issue, it is necessary not only to determine the origin, distribution and the concentration of HMI but also to rapidly (possibly in real-time) monitor their concentration levels in situ. Therefore, portable, low-cost and high performing analytical tools are urgently needed. Even though in the last decades many analytical tools and methodologies have been designed to this aim, there are still several open challenges. Compared with the traditional analytical techniques, such as atomic absorption/emission spectroscopy, inductively coupled plasma mass spectrometry and/or high-performance liquid chromatography coupled with electrochemical or UV–VIS detectors, bio- and biomimetic electrochemical sensors provide high sensitivity, selectivity and rapid responses within portable and user-friendly devices. In this review, the advances in HMI sensing in the last five years (2016–2020) are addressed. Key examples of bio and biomimetic electrochemical, impedimetric and electrochemiluminescence-based sensors for Hg2+, Cu2+, Pb2+, Cd2+, Cr6+, Zn2+ and Tl+ are described and discussed.

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Section: Coppermentioning

confidence: 99%

Section: Imprinted Polymersmentioning

confidence: 99%

Bio- and Biomimetic Receptors for Electrochemical Sensing of Heavy Metal Ions

Stortini

Baldo

Moro

et al. 2020

Sensors

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“…Owing to such unique combination of properties, PILs find applications [12] in diverse fields such as electrochemical supercapacitors [13], catalyst [14], gas adsorption [15], extraction [16,17,18,19], capillary electrochromatography [20], electrochemical sensors [21,22] and fluorescent determination [23]. In recent years, PIL-based materials prepared with IL monomer as modifiers for electrochemical sensors have been found to exhibit high sensitivity for analytes [24,25,26,27]. For example, Wang and co-workers prepared graphene oxide-poly(1-[3-(N-pyrrolyl) propyl]-3-butylimidazolium bromide) and used it as a modifier to construct an electrochemical sensor of bisphenol A detection [24].…”

Section: Introductionmentioning

confidence: 99%

“…In our previous work, we reported an electrochemical sensor with the composite of reduced graphene oxide and poly(1-vinyl-3-ethylimidazolium tetrafluoroborate) for sensitive detection of phenylethanolamine A [26]. Yu et al utilized the composite of dual hydroxyl-functionalized poly (ionic liquid) and 2,2’-Azinobis-(3-ethylbenzthiazoline-6-sulfonate) as the support to construct a ratiometric electrochemical biosensor for Cu 2+ determination [25].…”

Section: Introductionmentioning

confidence: 99%

“…Although monomer-based PIL composites as modifiers for electrochemical sensors have been extensively investigated [24,25,26,27], cross-linker based PILs or only PILs without any functionalization as modifiers for electrochemical sensors have rarely been studied [28,29,30,31]. This prompted us to carry out the current research, where we prepared a cross-linker-based PIL poly(1,4-butanediyl-3,3′-bis-l-vinylimidazolium dibromide) (poly([V 2 C 4 (mim) 2 ]Br 2 )) for sensitive electrochemical detection of 4-NP.…”

Section: Introductionmentioning

confidence: 99%

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A Cross-Linker-Based Poly(Ionic Liquid) for Sensitive Electrochemical Detection of 4-Nonylphenol

Dai

Zeng

et al. 2019

Nanomaterials

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In this study, we report a cross-linker-based poly(ionic liquid) (PIL) for the sensitive detection of 4-nonylphenol (4-NP). PIL was poly(1,4-butanediyl-3,3′-bis-l-vinylimidazolium dibromide) (poly([V2C4(mim)2]Br2)). Poly([V2C4(mim)2]Br2) was prepared via one-step free-radical polymerization. The poly([V2C4(mim)2]Br2) was characterized by infrared spectroscopy, Raman spectroscopy, thermal gravimetric analyzer and scanning electron microscope. The poly([V2C4(mim)2]Br2) was then drop-cast onto a glassy carbon electrode (GCE) to obtain poly([V2C4(mim)2]Br2)/GCE. In comparison with a bare GCE, poly([V2C4(mim)2]Br2)/GCE exhibited higher peak current responses for [Fe(CN)6]3−/4−, lower charge transfer resistance, and larger effective surface area. While comparing the peak current responses, we found the peak current response for 4-NP using poly([V2C4(mim)2]Br2)/GCE to be 3.6 times higher than a traditional cross-linker ethylene glycol dimethacrylate (EGDMA) based poly(EGDMA) modified GCE. The peak current of poly([V2C4(mim)2]Br2) sensor was linear to 4-NP concentration from 0.05 to 5 μM. The detection limit of 4-NP was obtained as 0.01 μM (S/N = 3). The new PIL based electrochemical sensor also exhibited excellent selectivity, stability, and reusability. Furthermore, the poly([V2C4(mim)2]Br2)/GCE demonstrated good 4-NP detection in environmental water samples.

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Contemporary electrochemical sensing and affinity biosensing to assist traces metal ions determination in clinical samples

Campuzano

Pedrero

Yáñez‐Sedeño

et al. 2021

Electrochemical Science Adv

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The determination of metals in clinical samples is an important challenge since their levels are relevant to ensure personal exposure to safe environments, as well as to assist in the prevention and treatment of disease. The low concentrations of metal ions in clinical samples and their coexistence with other metals and/or molecules of diverse nature implies the need for sensitive and selective analytical methodologies, which can be provided by conventional techniques. However, most of these techniques do not satisfy other highly demanded requirements such as high sampling frequency, multiplexed ability, and in-field analysis. In this context, the simplicity, speed of response, and compatibility with single or multiplexed point-of-care determinations have led to the successful incursion of electrochemical (bio)sensing into the clinical field for the determination of these analytes. Electrochemical (bio)devices have come on strong by exploiting and combining the unique attributes provided by electrochemical techniques (primarily voltammetry but also giving way to impedimetry in electrochemical affinity biosensing), electrode materials (Hg, Bi, Sb, Au, GCE, CPE, ITO, FTO), and substrates (conventional, screen-printed, flexible, paper, wearable or tattoo-type), suitable modifiers (nanomaterials, polymers, mesoporous films), bioreceptors (aptamers, peptides, biomolecular switches, DNAzymes, and DNA molecules), and nucleic acid amplification strategies (rolling circle and exonucleases-assisted target recycling). Therefore, the purpose of this review is to provide a bird's eye view of the state of the art, discussing the remarkable opportunities and potentialities demonstrated in the last decade by electrochemical sensors and electrochemical affinity biosensors for the analysis of metal ions in challenging clinical samples and forecasting future directions in this exciting field.

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Functionalized poly (ionic liquid) as the support to construct a ratiometric electrochemical biosensor for the selective determination of copper ions in AD rats

Cited by 47 publications

References 40 publications

Bio- and Biomimetic Receptors for Electrochemical Sensing of Heavy Metal Ions

Bio- and Biomimetic Receptors for Electrochemical Sensing of Heavy Metal Ions

A Cross-Linker-Based Poly(Ionic Liquid) for Sensitive Electrochemical Detection of 4-Nonylphenol

Contemporary electrochemical sensing and affinity biosensing to assist traces metal ions determination in clinical samples

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