Evolution of management in peritoneal surface malignancies

Canbay, Emel; Torun, Bahar Canbay; Torun, Ege Sinan; Yonemura, Yutaka

doi:10.5152/ucd.2016.3375

Cited by 2 publications

(3 citation statements)

References 64 publications

(59 reference statements)

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“…The indication for pulmonary metastasectomy has been based on Thomford's criteria (1) for a long time, but recently, it was increasingly extended to patients with multiple lesions, bilateral lesions, and solitary liver metastasis. Furthermore, the development of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy appears to contribute to better prospects of cure for patients with peritoneal dissemination (2). In this study, we included survival in patients who had been or were foreseen to be treated for peritoneal dissemination.…”

Section: Discussionmentioning

confidence: 99%

“…Peritoneal dissemination originating from gastrointestinal tract organs, pseudomyxoma peritonei, or ovarian cancer has for long been considered as a lethal disease with poor prognosis. Recently, however, new treatment methods have emerged, and nowadays even cure can be achieved with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in these patients (2). Consequently, we also need to analyze the prognosis of patients with peritoneal dissemination controlled by the treatments.…”

Section: Introductionmentioning

confidence: 99%

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Survival and prognostic factors in patients undergoing extended pulmonary metastasectomy

et al. 2020

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Extended pulmonary metastasectomy has become feasible in patients with extrapulmonary metastases and multiple or bilateral pulmonary metastases. Even peritoneal dissemination is considered to be curable in modern medicine. Therefore, it is necessary to analyze the prognosis of patients undergoing complete pulmonary metastasectomy. A total of 80 patients who underwent pulmonary resection for lung metastases were retrospectively analyzed. The eligibility criteria for the present study were as follows: i) the primary tumor was controlled; ii) if extrapulmonary metastases (including peritoneal dissemination) existed, these were controlled by local treatment or such treatment was planned; iii) the one to three months follow-up computed tomography (CT) following the first assessment revealed no increase of pulmonary metastatic disease; iv) pulmonary metastases could be resected completely. The overall 5-and 10-year survival rates were 71.7 and 41.5%, respectively. Applying the extended criteria for surgery, the present study demonstrated that pulmonary metastasectomy resulted in a good patient prognosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Survival and prognostic factors in patients undergoing extended pulmonary metastasectomy

et al. 2020

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“…The concept of IPC is still evolving (107). Understanding the molecular mechanisms in gastric cancer, developing new drugs that are more efficient in systemic and IPC as well as the targeted immunotherapy agents, and achieving acceptable perioperative morbidity, will possibly lead to better survival outcomes.…”

Section: Novel Approachesmentioning

confidence: 99%

Surgical management of metastatic gastric cancer: moving beyond the guidelines

Güner

Yıldırım

2019

Transl. Gastroenterol. Hepatol

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Gastric cancer remains a major health problem worldwide and has been considered as a dynamic disease that has potential to spread through various routes, such as hematogenous metastasis, lymphatic metastasis, or peritoneal seeding (1-4). Relatively aggressive behavior of gastric cancer may cause metastasis even in the early stages of the disease, and metastases may affect multiple focuses simultaneously (5,6).A few decades ago, the only treatment option for metastatic gastric cancer (MGC) was best supportive care. With the increasing use of cytotoxic chemotherapy agents in various types of cancer, chemotherapy has also been used for MGC, and various studies have demonstrated the superiority of systemic chemotherapy over best supportive

show abstract

Evolution of management in peritoneal surface malignancies

Cited by 2 publications

References 64 publications

Survival and prognostic factors in patients undergoing extended pulmonary metastasectomy

Survival and prognostic factors in patients undergoing extended pulmonary metastasectomy

Surgical management of metastatic gastric cancer: moving beyond the guidelines

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