Changes in symptoms of asthma and rhinitis by sensitization status over ten years in a cohort of young Chilean adults

García-Larsen, Vanessa; Potts, James; Giacco, Stefano Del; Bustos, Patricia; Díaz, Patricia; Amigo, Hugo; Oyarzún, M; Rona, Roberto

doi:10.1186/s12890-016-0273-6

Cited by 9 publications

(11 citation statements)

References 31 publications

(36 reference statements)

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“… 19 In contrast, the Study of Health in Pomerania (SHIP) study (in Germany) followed 3000 adults, aged 20–79 years, for about 6 years (1997/2001–2003/2006) and the prevalence of wheeze, waking with chest tightness and waking with shortness of breath fell (−0.7%, −1.9% and −1.0%, respectively) with some decrease in the prevalence of smoking (from 27.9% to 25.9%). 20 Cohort studies such as SHIP 20 and others in the UK, 21 Norway 22 and Chile 23 show that change in the prevalence of respiratory symptoms is strongly determined by smoking uptake and smoking cessation patterns in the study populations.…”

Section: Discussionmentioning

confidence: 98%

Prevalence of asthma-like symptoms with ageing

Jarvis

Newson

Janson

et al. 2017

Thorax

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BackgroundChange in the prevalence of asthma-like symptoms in populations of ageing adults is likely to be influenced by smoking, asthma treatment and atopy.MethodsThe European Community Respiratory Health Survey collected information on prevalent asthma-like symptoms from representative samples of adults aged 20–44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence were determined using generalised estimating equations (accounting for non-response through inverse probability weighting), followed by meta-analysis of centre level estimates.FindingsOver 20 years the prevalence of ‘wheeze’ and ‘wheeze in the absence of a cold’ decreased (−2.4%, 95% CI −3.5 to −1.3%; −1.5%, 95% CI −2.4 to −0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication and hay fever/nasal allergies increased (0.6%, 95% CI 0.1 to 1.11; 3.6%, 95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only). Decreases in these wheeze-related symptoms were largely seen in the group who gave up smoking, and were seen in those who reported hay fever/nasal allergies at baseline.InterpretationEuropean adults born between 1946 and 1970 have, over the last 20 years, experienced less wheeze, although they were more likely to report asthma attacks, use of asthma medication and hay fever. Decrease in wheeze is largely attributable to smoking cessation, rather than improved treatment of asthma. It may also be influenced by reductions in atopy with ageing.

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Section: Discussionmentioning

confidence: 98%

Prevalence of asthma-like symptoms with ageing

Jarvis

Newson

Janson

et al. 2017

Thorax

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“…Case-control and cohort studies were included if: 1) the main or secondary outcome was asthma, 2) the exposure of interest or one of the covariates was allergic rhinitis, 3) they reported a measure of association between allergic rhinitis and asthma such as Risk Ratio, Rate Ratio, Odds Ratio and their variance, standard error or 95% confidence intervals (CI), or provided enough raw data to calculate them. Whenever necessary, we contacted the authors to provide more information for the calculation of the effect measure or to clarify some methodologic aspects of the study 11, 12, 13, 14. Studies without comparison group (allergic rhinitis-free in cohort studies and asthma-free in case-control studies) and those that did not report measures of effect nor provide enough information for calculating them were excluded 13 .…”

Section: Methodsmentioning

confidence: 99%

“…Whenever necessary, we contacted the authors to provide more information for the calculation of the effect measure or to clarify some methodologic aspects of the study 11, 12, 13, 14. Studies without comparison group (allergic rhinitis-free in cohort studies and asthma-free in case-control studies) and those that did not report measures of effect nor provide enough information for calculating them were excluded 13 . If a study did not adjust for any factor, this study was not excluded but instead, we used its crude estimate 8, 15.…”

Section: Methodsmentioning

confidence: 99%

History of allergic rhinitis and risk of asthma; a systematic review and meta-analysis

Tohidinik

Mallah

Takkouche

2019

World Allergy Organization Journal

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BackgroundAllergic rhinitis has been suspected to be a risk factor for asthma in several studies but this association is not firmly established. The objective of this study was to synthesize the evidence of the association between allergic rhinitis and the risk of asthma through a systematic review and meta-analysis.MethodsWe performed a search in Medline, Scopus, ISI Proceedings databases and other databases from inception until February 2019, followed by manual search to identify potentially relevant case-control and cohort studies that reported relative risk estimates and confidence intervals of the association between allergic rhinitis and asthma. Cross-sectional studies were excluded. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed and random effects models and quality of studies was assessed through a modified version of the Newcastle-Ottawa scale.ResultsTwenty-nine eligible studies, 22 cohort and 7 case-control studies, with a total of 274489 subjects, were included in the meta-analysis. The results show that history of allergic rhinitis is significantly associated with the occurrence of asthma (OR = 3.82; 95% CI: 2.92–4.99). European studies showed a stronger association (OR = 4.35; (95% CI: 3.12–6.06) than non-European studies (OR = 2.75; 95% CI: 2.16–3.50), and case-control studies showed a stronger association (OR = 4.71; 95% CI: 3.58–6.17) than cohort studies (OR = 3.42; 95% CI: 2.60–4.50).ConclusionsThis meta-analysis shows that allergic rhinitis is strongly associated with asthma. Further prospective studies on the effect of treatment of allergic rhinitis on the development of asthma are needed. Relief of airway allergic manifestations may need dual control of allergic rhinitis and asthma.RegistrationPROSPERO database with registration number CRD42017055156.

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“…6,24,25 These increasing trends have been expected by the WHO 1 and have been well documented in many recent studies worldwide. 12,27 Although the results of our study could be owing to the selection of a homogenous group of young adults with possible accumulation of risk factors for allergic diseases, 7,13 a real increase in the prevalence over time, in comparison with previous Saudi reports, cannot be ruled out. It is noteworthy that similar high prevalence rates of allergic diseases have been reported among schoolchildren in the same region as our study site.…”

Section: Discussionmentioning

confidence: 63%

“…11 The prevalence of allergic diseases among children and adolescents has been studied extensively worldwide. [4][5][6][12][13][14] However, data are scarce regarding the burden of allergic diseases among adults and their risk factors. Moreover, the few epidemiological studies investigating the prevalence of allergic diseases among adults have lacked homogeneity in their adult cohorts.…”

Section: Introductionmentioning

confidence: 99%

Atopy and allergic diseases among Saudi young adults: A cross-sectional study

Alqahtani

2020

J Int Med Res

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In this cross-sectional study, we aimed to determine the prevalence of asthma and other allergic diseases among a homogenous group of students attending the health colleges of a Saudi university and to investigate the relationship between their atopy profile and associated clinical symptoms of allergic diseases. Methods: A total of 222 students completed the International Study of Asthma and Allergies in Childhood questionnaire and underwent skin prick testing (SPT) using a standardized panel of allergenic extracts. Results: Overall prevalence of physician-diagnosed allergic diseases was 27% for bronchial asthma (BA), 13.1% for atopic dermatitis (AD), and 5% for allergic rhinitis (AR). Atopy was present in 90 (40.5%) students. Students with atopic disease were more likely to have physician-diagnosed BA, AR, and AD. Atopy and polysensitization was more frequent among male than female students. SPT results were positive in 20.8% of participants for Bermuda grass, 18.9% for cat fur, and 12.7% for Dermatophagoides pteronyssinus. Conclusion: The prevalence of atopy and allergic diseases in Saudi young adults is high and worrisome. Comorbid allergic diseases were more prevalent among our participants with atopic disease. Determination of allergen sensitization patterns in patients with atopic disease is crucial for selecting proper preventive and therapeutic strategies.

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Changes in symptoms of asthma and rhinitis by sensitization status over ten years in a cohort of young Chilean adults

Cited by 9 publications

References 31 publications

Prevalence of asthma-like symptoms with ageing

Prevalence of asthma-like symptoms with ageing

History of allergic rhinitis and risk of asthma; a systematic review and meta-analysis

Atopy and allergic diseases among Saudi young adults: A cross-sectional study

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