Forging Collaborative Relationships in Brazil: From AIDS to ZIKV

Next-generation sequencing technologies, exponential increases in the availability of virus genomic data, and ongoing advances in phylogenomic methods have made genomic epidemiology an increasingly powerful tool for public health response to a range of mosquito-borne virus outbreaks. In this review, we offer a brief primer on the scope and methods of phylogenomic analyses that can answer key epidemiological questions during mosquito-borne virus public health emergencies. We then focus on case examples of outbreaks, including those caused by dengue, Zika, yellow fever, West Nile, and chikungunya viruses, to demonstrate the utility of genomic epidemiology to support the prevention and control of mosquito-borne virus threats. We extend these case studies with operational perspectives on how to best incorporate genomic epidemiology into structured surveillance and response programs for mosquito-borne virus control. Many tools for genomic epidemiology already exist, but so do technical and nontechnical challenges to advancing their use. Frameworks to support the rapid sharing of multidimensional data and increased cross-sector partnerships, networks, and collaborations can support advancement on all scales, from research and development to implementation by public health agencies.

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Genomic Epidemiology as a Public Health Tool to Combat Mosquito-Borne Virus Outbreaks

Pollett

Fauver

Berry

et al. 2019

The Journal of Infectious Diseases

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Forging Collaborative Relationships in Brazil: From AIDS to ZIKV

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Genomic Epidemiology as a Public Health Tool to Combat Mosquito-Borne Virus Outbreaks

Genomic Epidemiology as a Public Health Tool to Combat Mosquito-Borne Virus Outbreaks

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