Silicon in broiler drinking water promotes bone development in broiler chickens

Sgavioli, Sarah; Domingues, Carla Heloísa de Faria; Castiblanco, Diana Maryuri Correa; Praes, M. F. F. M.; Andrade-Garcia, Giuliana M; Santos, Elaine Talita; Artoni, Silvana Martinez Baraldi; Garcia, Rodrigo Arroyo; Junqueira, Otto Mack

doi:10.1080/00071668.2016.1206190

Cited by 10 publications

(15 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Measurement of bone-related parameters is the principal method for the assessment of bone growth 36 . Thus, these findings revealed that broilers are highly susceptible to leg diseases, which may be associated with faster weight gain than bone growth from the legs accompanied with shortage of the vascular invasion 37 .…”

Section: Resultsmentioning

confidence: 90%

“…Moreover, production speed of the RBC and Hb decreased with age, which indicates that the oxygen and nutrients in the blood may not be efficiently transported to the chondrocytes. Therefore, the growth rate of BW is not synchronized with that of the bones and blood vessels, which is the main trigger for TD 37 . Our previous studies have found that no case of TD has been reported in Tibetan chickens, which have abundant vascular distribution in the TGP 44 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

Huang

Zhang

et al. 2018

Sci Rep

View full text Add to dashboard Cite

Tibial dyschondroplasia (TD) is the most-prevalent leg disorder in fast-growing chickens; it is intractable and characterized by abnormal endochondral bone formation of proximal tibial growth-plates (TGPs). Previous studies have shown that bone is a highly vascularized tissue dependent on the coordinated coupling between angiogenesis and osteogenesis, but the underlying mechanisms of bone formation and bone remodeling are poorly defined in TD chickens. Here, we observed that inhibition of vasculogenesis and angiogenesis remarkably impaired vascular invasion in the hypertrophic chondrocyte zone of the TGPs, resulting in the massive death of chondrocytes due to a shortage of blood vessels and nutrients. Moreover, the balance of the OPG (osteoprotegerin)/RANKL (receptor activator of nuclear factor-kB ligand) system is also severely disrupted during the osteogenesis process while coupling with angiogenesis, both of which eventually lead to abnormal endochondral bone formation in TD chickens. Thus, the process of vascular formation in endochondral bone appears to initiate the pathological changes in TD, and improvement of this process during coupling with osteogenesis may be a potential therapeutic approach to treat this intractable disease.

show abstract

Section: Resultsmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

Huang

Zhang

et al. 2018

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Higher meat yield in broiler is a desirable trait but has negative influence on the development of its bones (Hafeez et al, 2014). Rapid growth rate and higher muscle mass results in metabolic disorders, leading to leg problems or weakness, and difficulties in locomotion (Sgavioli et al, 2016). Bone length, weight and ash percentage are good indicators of the bone health (Ziaie et al, 2011), which in turn depend on its mineral content especially calcium (Hafeez et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Effect of Moringa Oleifera Leaf Powder Supplementation on Pectoral Muscle Quality and Morphometric Characteristics of Tibia Bone in Broiler Chickens

Faseehur-Rehman

Zaneb

Masood

et al. 2018

Braz. J. Poult. Sci.

View full text Add to dashboard Cite

Although in-feed antibiotics work for broiler chicken´s growth, they are a source of public health hazard. Therefore, there is a need for alternates which can act as growth promoter without deleterious effects on the health of meat consumers. Moringa oleifera is one such phytobiotic which is reported to possess antimicrobial and immunomodulatory properties. This study investigated the effect of Moringa oleifera leaf powder (MOLP) supplementation on meat quality and bone morphometry of broiler. One-day-old chicks (n=100), divided into five groups (four replicates with n=5), were fed a basal diet (control group) or same diet supplemented with 6, 9, 12 or 15 g/kg MOLP. On d-35, two birds per replicate were euthanized to collect samples of breast muscle, blood and tibia bone. The MOLP supplementation significantly increased pH of breast muscle and ash percentage of tibia bone. The diameter of breast muscle fibres and also weight and weight length index of tibia bone significantly increased with 12 and 15 g/kg MOLP. The water holding capacity (WHC) of breast muscle was significantly higher with 9 and 15 g/kg MOLP; whereas robusticity index of tibia bone significantly decreased with 12 and 15 g/kg MOLP inclusion compared to the control group. In conclusion, dietary supplementation of Moringa oleifera leaf powder (12g/kg) increased pH, water holding capacity, and muscle fibre diameter of breast muscle and also weight, ash percentage and density indices of tibia bone in broiler chickens.

show abstract

“…The contrasting reported conclusions on the efficacy of silicon supplementation in reducing the incidence and severity of lameness may be due to differing physico-chemical composition and properties of different silicon supplements, which were not fully described in the published studies. Silicon (no source description) supplemented via the water available to broiler chickens has been shown to have no significant effect on bone breaking strength and bone density but did result in a change in the mineral profile of the bones with increases in phosphorus, zinc, copper, manganese and ash being observed 14 . The majority of naturally occurring silicon is present in highly stable minerals as silica and silicates.…”

Section: Introductionmentioning

confidence: 99%

Bioavailability of a novel form of silicon supplement

Scholey

Belton

Burton

et al. 2018

Sci Rep

View full text Add to dashboard Cite

In this study, we assessed uptake and potential efficacy of a novel, pH neutral form of silicon supplement in vitro and using broiler chickens as a model species. In vitro bioavailability of this supplement was significantly higher than other commercial supplements tested, all of which claim available silica content. To confirm bioavailability of the new supplement in vivo, a broiler chick feeding trial reported blood uptake that was significantly higher than a Bamboo-derived silicon supplement. We assessed dose response of the novel supplement in a further study with increased dose related levels of silicon being detected in the blood and tibia. We found tibia and foot ash residue as a percentage of dry mass was higher with inclusion of the novel supplement in the diet, particularly in young birds and that this was followed by significant increase in tibia breaking strength. This novel supplement may therefore have applications in the improvement of bone integrity, with implications for the reduction of lameness in broilers. These results indicate the novel silica supplement is readily absorbed in chicks, and transported in the blood supply to sites such as the skeleton due to it being present in a non-condensed, monomeric form. There is potential for wider application of this silica supplement in other species where bone breakages are a problem, including high performance sport.

show abstract

Silicon in broiler drinking water promotes bone development in broiler chickens

Cited by 10 publications

References 18 publications

Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

Effect of Moringa Oleifera Leaf Powder Supplementation on Pectoral Muscle Quality and Morphometric Characteristics of Tibia Bone in Broiler Chickens

Bioavailability of a novel form of silicon supplement

Contact Info

Product

Resources

About