Validation Study of the Korean Version of the Brief Clinical Form of the Neuropsychiatric Inventory

Abstract

Aim: This study aims to provide a brief questionnaire form of the Neuropsychiatric Inventory (NPI-Q) in Korean translated from the original NPI-Q that is intended for the evaluation of behavioral and psychological symptoms of dementia in routine clinical practice. Patients and Methods: We developed a Korean version of the NPI-Q (KNPI-Q) and compared subitems with those of the Korean version of the NPI (KNPI) in 63 dementia patients; 47 patients had been diagnosed with Alzheimer's disease with dementia, 8 with vascular dementia, and 8 with dementia with Lewy body disease. The diagnosis was based on the National Institute of Neurological and Communicative Disorders and Stroke - Alzheimer's Disease and Related Disorders Association criteria for possible and probable Alzheimer's disease and the International Statistical Classification of Diseases and Related Health Problems, 10th revision, criteria for vascular dementia and other dementing diseases. All patients received the Korean version of the Mini-Mental State Examination and the Clinical Dementia Rating within 1 month of the KNPI-Q. Results: Test-retest reliability of the KNPI-Q using a Pearson correlation index was r = 0.89 for the total symptom scale and r = 0.90 for the distress scale. The prevalence of analogous symptom ratings differed by less than 6.7%. Convergent validity between the KNPI-Q and the NPI using a Pearson correlation index was r = 0.879 for the total symptom scale and r = 0.92 for the distress scale. Conclusions: The KNPI-Q is a reliable and brief instrument that can be employed for screening in the evaluation of neuropsychiatric symptoms of dementia and associated caregiver distress. It may be suitable for use in general clinical practice and could be administered as a brief neuropsychiatric interview.

Neuropsychiatric symptoms after moderate-to-severe traumatic brain injury in Vietnam: Assessment, prevalence, and impact on caregivers

“…In addition, the V-NPI had good convergent validity as it showed expected concordances with validated measures of behavioral and emotional states (i.e., the V-FrSBe and V-DASS-21_Patient). These findings are consistent with other studies on the NPI in different languages, such as Spanish (Castaño Monsalve et al, 2012), Italy (Ciurli et al, 2011), Chinese (Leung et al, 2001), and Korean (Kim et al, 2016).…”

The Neuropsychiatric Inventory: Development and Applications

“…The NPI has shown good reliability across translation into multiple languages including Chinese, [21][22][23][24] Chilean Spanish, 25 Korean, 26,27 Turkish, 28 Brazilian Portugese, 6,29 European Portugese, 30 Farsi, 31 Icelandic, 32 Japanese, [33][34][35] Norwegian, 36 Polish, 37 Greek, 38 Nigerian, 39 Danish, 40 Dutch, 41 Italian, 42 and European Spanish. 43,44 The validity of the NPI in non-Western cultures has rarely been rigorously examined and remains an area to be researched.…”

Detecting agitation and aggression in persons living with dementia: a systematic review of diagnostic accuracy

“…They were conducted in North America ( n = 11) [ 25 , 31 , 33 – 35 , 40 , 48 , 49 , 51 , 55 , 57 ], Asia ( n = 7) [ 32 , 38 , 39 , 47 , 52 , 53 , 56 ] South America ( n = 1) [ 34 ], Europe ( n = 8) [ 22 , 34 , 36 , 43 – 46 , 54 , 58 ], and Australia ( n = 1) [ 41 ]. Furthermore, four studies did not report their location [ 16 , 37 , 42 , 50 ]. The studies were published between 1989 and 2023 [ 42 , 58 ].…”

“…The types of dementia reported include Alzheimer’s Disease, Vascular, Lewy Body, or general dementia not otherwise specified. However, multiple articles did not report the type ( n = 11) [ 16 , 22 , 25 , 35 , 41 – 44 , 49 , 56 , 58 ] or severity ( n = 19) [ 25 , 32 , 33 , 35 , 37 , 39 – 48 , 53 , 54 , 56 , 57 ] of dementia in their population.…”