Surgical challenges in the treatment of a giant renal cell carcinoma with atypical presentation: A case report

Abstract

HighlightsDescription of the largest renal cell carcinoma ever resected.Unusual presentation led to a delay in diagnosis.Tumor size necessitated careful intraoperative maneuvers.Major resections are possible in community hospital with multidisciplinary team.

A case of the world’s largest renal cell carcinoma

“…Preservation of capsule of gigantic renal mass ensures complete resection. 7 The cause of death in our case is due to the ultimate nature of the tumor (mostly necrotic and liquefied cystic mass with an area of weak wall) as well as complicated presurgical conditions (malnutrition, anemia, ischemic bowel, duodenal ulcer perforation, and hypotension).…”

“…We performed extensive literature search using the PubMed database for case reports of a large renal tumor published in the English language. Table 1 summarizes cases of extremely large malignant renal tumor including our case 4–12 . Overall, large renal tumors are malignant neoplasms, such as RCC subtypes, malignant SFT, and leiomyosarcoma, with benign angiomyolipoma being an exception 5 .…”

“…Table 1 summarizes cases of extremely large malignant renal tumor including our case. [4][5][6][7][8][9][10][11][12] Overall, large renal tumors are malignant neoplasms, such as RCC subtypes, malignant SFT, and leiomyosarcoma, with benign angiomyolipoma being an exception. 5 Currently, the largest reported renal tumor is 11.5 kg, a chromophobe RCC reported in 2009.…”

Radical nephrectomy for a giant chromophobe renal cell carcinoma diagnosed > 17 years previously: A case report and literature review

“…However, case reports indicate that males are more prone to developing giant masses than females. 5,[7][8][9][10] Our patient underwent surgical treatment > 17 years after her tumor was discovered primarily because she had been asymptomatic. To the best of our knowledge, this is the longest reported survival time in a patient with kidney cancer who did not receive any treatment.…”

Surgical treatment of giant renal tumor: a case report

“…В последнее время достигнуты значительные успехи в создании ряда новых препаратов и подходов к лечению прогрессирующего ПКР. Тем не менее лечение ПКР преимущественно хирургическое, так как 5-летняя выживаемость пациентов без удаления опухоли составляет примерно 10 % [2]. По данным онкологического регистра, общая заболеваемость ПКР в США с 1983 г. увеличилась с 7,1 до 10,8 случая на 100 тыс.…”