“…Polygodial. 1 H NMR (CDCl 3 , 500 MHz) δ 9.50 (d, J = 4.4 Hz, H-11), 9.43 (s, H-12), 7.12 (ddd, J = 7.5, 2.2, and 2.1 Hz, H-7), 2.78 (m, H-9), 2.49 (m, H-6α), 2.30 (m, H-6β), 1.83 (m, H-1β), 1.52−1.47 (m, H-2), 1.45 (m, H-3β), 1.36 (m, H-1α), 1.23 (m, H-5), 1.20 (m, H-3α), 0.93 (s, H-14), 0.92 (s, H-15), 0.90 (s, H-13); 13 (12), 163 (18), 145 (16), 135 (22), 121 (100), 110 (81), 91 (64), 79 (47), 67 (48) Sponge Disc Implantation and Polygodial Treatment. Polyether-polyurethane sponge discs (Vitafoam Ltd., Manchester, UK), 5 mm thick × 8 mm diameter, were used as the implanted material to create the inflammatory environment.…”