Short term effects of small incision lenticule extraction surgery on corneal endothelium

Wang, Dan Yang; Liu, Man Li; Chen, Yi Le; Zhang, Xiao Ying; Xu, Yang; Wang, Jian Chao; To, Chi Ho; Wang, Jingguo; Liu, Quan

doi:10.18240/ijo.2016.04.09

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…Wang et al 16 assessed the effects of small incision lenticule extraction (SMILE) surgery on the corneal endothelium at one day, one week, and one month postoperatively on 47 eyes who received SMILE surgery. The corneal endothelium was analyzed.…”

Section: Discussionmentioning

confidence: 99%

Comparison Between the Effect of Femtosecond Laser in situ Keratomileusis (FS-LASIK) and Femtosecond Small Incision Lenticule Extraction (FS-SMILE) on the Corneal Endothelium

Shaaban¹,

Badran²

2020

OPTH

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Purpose: To compare the effect of FS-LASIK and FS-SMILE on the corneal endothelial cell density (ECD) and morphology. Patients and Methods: This is a prospective, cohort observational study that included 80 eyes of two equal groups of patients. Forty eyes were subjected to the FS-LASIK, and 40 eyes were subjected to the FS-SMILE. In both groups, patients, age ranged between 19 and 37 years with myopia ranges from −0.75 to −9.00 diopters (D) and astigmatism up to −3.00D. The ECD, coefficient of variation (CV), and hexagonality (HEX) in both groups were compared over six months. Specular microscopy was used to evaluate the corneal endothelium throughout the study. Results: In both groups, ECD showed a statistically significant decrease while CV showed a statistically significant increase in the first month postoperatively. The FS-SMILE had more impact on both ECD and CV until the third and six months, respectively. Hexagonality showed a significant decrease in both groups throughout the whole study. In both groups, no vision-threatening complications occurred, and no eyes developed any corneal complications over a six-month follow-up period. Conclusion: Although the ECD, CV, HEX are statistically affected in both FS-LASIK and FS-SMILE groups, both procedures have no significant adverse effects on the ECD and morphology. The impact of the FS-SMILE group may be due to the deeper penetration of the femto laser in the corneal tissue compared to the FS-LASIK. The closer the femto laser to the endothelium, the more exposure to the shock waves and heat energy, although minimal but it can cause collateral damage to this layer. The effects of FS-SMILE surgery on corneal endothelial cells and morphology need further investigations.

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Section: Discussionmentioning

confidence: 99%

Comparison Between the Effect of Femtosecond Laser in situ Keratomileusis (FS-LASIK) and Femtosecond Small Incision Lenticule Extraction (FS-SMILE) on the Corneal Endothelium

Shaaban¹,

Badran²

2020

OPTH

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“… 18 , 19 There are some reports that SMILE has no adverse effects on the corneal endothelium. 20 , 21 Kamiya et al 22 reported there was no significant difference in ECD after femtosecond laser-assisted keratoplasty (FLAK) and after conventional penetrating keratoplasty, even though energy was higher (300 nJ in FLAK vs 140 nJ in our study), spot distance was narrower (3.0 µm in FLAK vs 4.0 µm in our study), and depth of laser was deeper (vertically full thickness in FLAK vs minimal residual stromal bed 310 µm in our study). Park et al 23 reported a positive outcome after SMILE in a patient with posterior polymorphic corneal dystrophy, which has been described as a contraindication of LASIK 24 because of the risk of corneal decompensation.…”

Section: Discussionmentioning

confidence: 99%

Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae

Kim¹,

Chung²

2020

OPTH

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Short term effects of small incision lenticule extraction surgery on corneal endothelium

Abstract: SMILE has no significant adverse effects on the corneal ECD and morphology during 1mo follow-up time.

Cited by 2 publications

References 20 publications

<p>Comparison Between the Effect of Femtosecond Laser in situ Keratomileusis (FS-LASIK) and Femtosecond Small Incision Lenticule Extraction (FS-SMILE) on the Corneal Endothelium</p>

<p>Comparison Between the Effect of Femtosecond Laser in situ Keratomileusis (FS-LASIK) and Femtosecond Small Incision Lenticule Extraction (FS-SMILE) on the Corneal Endothelium</p>

<p>Small Incision Lenticule Extraction (SMILE) in Patients with Corneal Guttae</p>

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