Quick reference guide to the new oral anticoagulants

Abstract

After the commissioning of new oral anticoagulants for the treatment and prevention of thrombosis, these medications are now widely used within clinical settings. Increasing numbers of patients present to the health services on anticoagulant medications, and it is therefore imperative for surgeons to be aware of the new therapeutic treatments available and how patients will benefit from such interventions. This review highlights the most pertinent learning points for surgeons regarding the indications, pharmacokinetics, and perioperative management of these new oral medications, as a quick reference guide.

Physicians in Promoting Stroke Awareness: A Multidisciplinary Effort

“…The patients can be first time stroke sufferers or people who have previously survived a stroke. The patients with a history of stroke or atrial fibrillation with or without intervention usually have a regimen of anticoagulants and/or anti-platelets medications [11][12][13][14]. 4) The variety of perioperative physicians.…”

“…The highest risk factors for onset of new strokes or recurrence of perioperative strokes are a prior history of transient ischemic attack or stroke and an existing atrial fibrillation [3,8,12]. Patients with stroke history or atrial fibrillation with or without intervention will usually take regular anticoagulants [11,12,13]. If coagulation and anticoagulation are not well adjusted, stroke or hemorrhage may happen intraoperatively [11,12,14,16].…”

“…Patients with stroke history or atrial fibrillation with or without intervention will usually take regular anticoagulants [11,12,13]. If coagulation and anticoagulation are not well adjusted, stroke or hemorrhage may happen intraoperatively [11,12,14,16]. The following are critical in preventing perioperative stroke and have to be carefully considered and individualized: 1) Medication strategy for the prevention of thrombosis/embolism and the management of bleeding risk.…”