Objectives
The current psoriatic arthritis (PsA) Core Domain Set defines core
domains to be measured in randomized controlled trials (RCTs) and
longitudinal observational studies (LOS) and was published in 2006. At the
Outcome Measures in Rheumatology (OMERACT) meeting in 2014, researchers,
clinicians and patients unanimously voted for updating the PsA Core Domain
Set to include the patient perspective in accordance with OMERACT Filter
2.0. Herein we report the proceedings of the PsA Workshop at the OMERACT
meeting in 2016 including studies presented in the plenary, results of
breakout group discussions, and final voting and endorsement of the 2016
updated PsA Core Domain Set.
Methods
We conducted research to develop the updated PsA Core Domain Set. At
OMERACT 2016 this work was presented, discussed in breakout groups and the
updated PsA core domain set was voted on and endorsed by OMERACT
participants.
Results
The updated PsA Core Domain Set includes: musculoskeletal disease
activity, skin disease activity, fatigue, pain, patient global, physical
function, health related quality of life and systemic inflammation which are
recommended for all RCTs and LOS). Economic cost, emotional well-being,
participation and structural damage are important but not required in all
RCTs and LOS. Independence, sleep, stiffness and treatment burden on the
research agenda.
Conclusion
The updated PsA Core Domain Set was endorsed at OMERACT 2016. Next
steps for the PsA working group include evaluation of available outcome
measures for each of the core domains and development of a PsA core outcome
measurement set.